The DOI matches its Crossref record.
Crystal structure of interleukin 8: symbiosis of NMR and crystallography.
Open accessAbstract
The crystal structure of a host defense system chemotactic factor, interleukin 8, has been solved by molecular replacement using as a model the solution structure derived from nuclear magnetic resonance experiments. The structure was refined with 2 A x-ray data to an R factor of 0.187 (0.217 at 1.6 A). A comparison indicates some potential differences between the structure in solution and in the crystalline state. Our analysis also predicts that residues 4 through 9 on the amino terminus and the beta-bend, which includes His-33, may be important for receptor binding.
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Citations
Cited by
Structure, Function, and Inhibition of Chemokines
Fernandez, E. J., & Lolis, E. (2002) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.42.091901.115838 · Cited by 609
Neutrophil Gelatinase B and Chemokines in Leukocytosis and Stem Cell Mobilization
Starckx, S., Van den Steen, P. E., Wuyts, A., Van Damme, J., & Opdenakker, G. (2002) · Leukemia & Lymphoma · doi:10.1080/10428190290005982 · Cited by 49
Metadata
- Authors
- Baldwin, E. T., Weber, I. T., St Charles, R., Xuan, J. C., Appella, E., Yamada, M., Matsushima, K., Edwards, B. F., Clore, G. M., & Gronenborn, A. M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1991-01-15
- Volume
- 88
- Issue
- 2
- Pages
- 502-506
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2053902929
- Cited by
- 354
- References
- 0
- FWCI
- 25.18
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
