The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A gene expression screen.
Open accessAbstract
A gene expression screen identifies mRNAs that differ in abundance between two mRNA mixtures by a subtractive hybridization method. The two mRNA populations are converted to double-stranded cDNAs, fragmented, and ligated to linkers for polymerase chain reaction (PCR) amplification. The multiple cDNA fragments isolated from any given gene can be treated as alleles in a genetic screen. Probability analysis of the frequency with which multiple alleles are found provides an estimation of the total number of up- and down-regulated genes. We have applied this method to genes that are differentially expressed in amphibian tadpole tail tissue in the first 24 hr after thyroid hormone treatment, which ultimately induces tail resorption. We estimate that there are about 30 up-regulated genes; 16 have been isolated.
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Cites
Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.
Lau, L. F., & Nathans, D. (1985) · The EMBO Journal · doi:10.1002/j.1460-2075.1985.tb04057.x · Cited by 567
Cited by
Brown, D. D., & Cai, L. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.03.021 · Cited by 498
Self-citationFerritoid, a Tissue-specific Nuclear Transport Protein for Ferritin in Corneal Epithelial Cells
Millholland, J. M., Fitch, J. M., Cai, C. X., Gibney, E. P., Beazley, K. E., & Linsenmayer, T. F. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210050200 · Cited by 30
Metadata
- Authors
- Wang, Z., & Brown, D. D.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1991-12-15
- Volume
- 88
- Issue
- 24
- Pages
- 11505-11509
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2039455433
- Cited by
- 347
- References
- 1
- FWCI
- 4.31
- Type
- journal article
- Language
- en
- Open access
- green
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- Wang, Z., & Brown, D. D. (1991). A gene expression screen. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.88.24.11505
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