The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Adenovirus as an expression vector in muscle cells in vivo.
Open accessAbstract
Attempting gene transfer in muscle raises difficult problems: the nuclei of mature muscle fibers do not undergo division, thus excluding strategies involving replicative integration of exogenous DNA. As adenovirus has been reported to be an efficient vector for the transfer of an enzyme encoding gene in mice, we decided to explore its potential for muscle cells. Advantages of adenovirus vectors are their independence of host cell replication, broad host range, and potential capacity for large foreign DNA inserts. We constructed a recombinant adenovirus containing the beta-galactosidase reporter gene under the control of muscle-specific regulatory sequences. This recombinant virus was able to direct expression of the beta-galactosidase in myotubes in vitro. We report its in vivo expression in mouse muscles up to 75 days after infection. The efficiency and stability of expression we obtained compare very favorably with other strategies proposed for gene or myoblast transfer in muscle in vivo.
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Cites
Direct Gene Transfer into Mouse Muscle in Vivo
Wolff, J. A., Malone, R. W., Williams, P., Chong, W., Acsadi, G., Jani, A., & Felgner, P. L. (1990) · Science · doi:10.1126/science.1690918 · Cited by 4,173
Very mild muscular dystrophy associated with the deletion of 46% of dystrophin
England, S. B., Nicholson, L. V. B., Johnson, M. A., Forrest, S. M., Love, D. R., Zubrzycka-Gaarn, E. E., Bulman, D. E., Harris, J. B., & Davies, K. E. (1990) · Nature · doi:10.1038/343180a0 · Cited by 623
Cited by
Transfer of a foreign gene into the brain using adenovirus vectors
Akli, S., Caillaud, C., Vigne, E., Stratford-Perricaudet, L. D., Poenaru, L., Perricaudet, M., Kahn, A., & Peschanski, M. R. (1993) · Nature Genetics · doi:10.1038/ng0393-224 · Cited by 532
Packaging capacity and stability of human adenovirus type 5 vectors
Bett, A. J., Prevec, L., & Graham, F. L. (1993) · Journal of Virology · doi:10.1128/jvi.67.10.5911-5921.1993 · Cited by 472
Development of Approaches to Improve Cell Survival in Myoblast Transfer Therapy
Qu, Z., Balkir, L., van Deutekom, J. C. T., Robbins, P. D., Pruchnic, R., & Huard, J. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.5.1257 · Cited by 462
Morral, N., O’Neal, W., Rice, K., Leland, M., Kaplan, J., Piedra, P. A., Zhou, H., Parks, R. J., Velji, R., Aguilar-Córdova, E., et al. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.22.12816 · Cited by 409
Recombinant Adeno-Associated Viral Vectors Mediate Long-Term Transgene Expression in Muscle
Clark, K. R., Sferra, T. J., & Johnson, P. R. (1997) · Human Gene Therapy · doi:10.1089/hum.1997.8.6-659 · Cited by 153
Metadata
- Authors
- Quantin, B., Perricaudet, L. D., Tajbakhsh, S., & Mandel, J. L.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1992-04
- Volume
- 89
- Issue
- 7
- Pages
- 2581-2584
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2036650398
- Cited by
- 296
- References
- 2
- FWCI
- 18.81
- Type
- journal article
- Language
- en
- Open access
- green
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- Quantin, B., Perricaudet, L. D., Tajbakhsh, S., & Mandel, J. L. (1992). Adenovirus as an expression vector in muscle cells in vivo. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.89.7.2581
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