The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization.
Open accessAbstract
Comparative genomic hybridization was applied to 5 breast cancer cell lines and 33 primary tumors to discover and map regions of the genome with increased DNA-sequence copy-number. Two-thirds of primary tumors and almost all cell lines showed increased DNA-sequence copy-number affecting a total of 26 chromosomal subregions. Most of these loci were distinct from those of currently known amplified genes in breast cancer, with sequences originating from 17q22-q24 and 20q13 showing the highest frequency of amplification. The results indicate that these chromosomal regions may contain previously unknown genes whose increased expression contributes to breast cancer progression. Chromosomal regions with increased copy-number often spanned tens of Mb, suggesting involvement of more than one gene in each region.
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Cites
Amplification of a gene encoding a p53-associated protein in human sarcomas
Oliner, J. D., Kinzler, K. W., Meltzer, P. S., George, D. L., & Vogelstein, B. (1992) · Nature · doi:10.1038/358080a0 · Cited by 1,949
ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization
Kallioniemi, O. P., Kallioniemi, A., Kurisu, W., Thor, A., Chen, L. C., Smith, H. S., Waldman, F. M., Pinkel, D., & Gray, J. W. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.12.5321 · Cited by 555
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Cited by
AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer
Anzick, S. L., Kononen, J., Walker, R. L., Azorsa, D. O., Tanner, M. M., Guan, X.-Y., Sauter, G., Kallioniemi, O.-P., Trent, J. M., & Meltzer, P. S. (1997) · Science · doi:10.1126/science.277.5328.965 · Cited by 1,639
Self-citationAutophagy suppresses tumor progression by limiting chromosomal instability
Mathew, R., Kongara, S., Beaudoin, B., Karp, C. M., Bray, K., Degenhardt, K., Chen, G., Jin, S., & White, E. (2007) · Genes & Development · doi:10.1101/gad.1545107 · Cited by 938
Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer
(1996) · Advances in cancer research · doi:10.1016/s0065-230x(08)60352-8 · Cited by 752
Molecular Cytogenetic Analysis of Spitz Nevi Shows Clear Differences to Melanoma
Bastian, B. C., Wesselmann, U., Pinkel, D., & LeBoit, P. E. (1999) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1999.00787.x · Cited by 329
Self-citationCollins, C., Rommens, J. M., Kowbel, D., Godfrey, T., Tanner, M., Hwang, S.-I., Polikoff, D., Nonet, G., Cochran, J., Myambo, K., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.15.8703 · Cited by 300
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Metadata
- Authors
- Kallioniemi, A., Kallioniemi, O. P., Piper, J., Tanner, M., Stokke, T., Chen, L., Smith, H. S., Pinkel, D., Gray, J. W., & Waldman, F. M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1994-03-15
- Volume
- 91
- Issue
- 6
- Pages
- 2156-2160
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2061206375
- Cited by
- 739
- References
- 2
- FWCI
- 27.57
- Type
- journal article
- Language
- en
- Open access
- green
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