Molecular cloning and characterization of chitinase genes from Candida albicans.

McCreath, K J; Specht, C A; Robbins, P W

doi:10.1073/pnas.92.7.2544

Molecular cloning and characterization of chitinase genes from Candida albicans.

Chitinase (EC 3.2.1.14) is an important enzyme for the remodeling of chitin in the cell wall of fungi. We have cloned three chitinase genes (CHT1, CHT2, and CHT3) from the dimorphic human pathogen Candida albicans. CHT2 and CHT3 have been sequenced in full and their primary structures have been a…