The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding
Feder, John N., Penny, David M., Irrinki, Alivelu, Lee, Vince K., Lebrón, José A., Watson, Nicole, Tsuchihashi, Zenta, Sigal, Elliott, Bjorkman, Pamela J., Schatzman, Randall C.·1998·Proceedings of the National Academy of Sciences
Cited by (824)
Items 401–500 of 824
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- HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4ASang Yong Lee, Siying Liu, Ryan M. Mitchell, Becky Slagle‐Webb, Young‐Soo Hong, Jonas M. Sheehan, James R. Connor · 2010 · International Journal of Cancer
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- Identification of an endogenous RNA transcribed from the antisense strand of the HFE geneAgnès Thénié · 2001 · Human Molecular Genetics
- Transferrin Receptor Mutation Analysis in Hereditary Hemochromatosis PatientsZenta Tsuchihashi, Sherry L. Hansen, Leah Quintana, Gregory S. Kronmal, Felipa Mapa, John N. Feder, Roger K. Wolff · 1998 · Blood Cells Molecules and Diseases
- Transferrin stimulates iron absorption, exocytosis, and secretion in cultured intestinal cellsMarco Tulio Núñez, Victoria Tapia · 1999 · American Journal of Physiology-Cell Physiology
- Inborn errors of metabolism: ironMark Worwood · 1999 · British Medical Bulletin
- Accelerated Transferrin Degradation in HFE-Deficient Mice Is Associated with Increased Transferrin SaturationChaity Chaudhury, Jonghan Kim, Samina Mehnaz, Manzoor A Wani, Tatiana M. Oberyszyn, C. L. Bronson, Sudhasri Mohanty, William L. Hayton, John M. Robinson, Clark L. Anderson · 2006 · Journal of Nutrition
- Iron potentiates acetaminophen-induced oxidative stress and mitochondrial dysfunction in cultured mouse hepatocytes.Mi-Sun Moon, J. Richie, H. Isom · 2010 · Toxicological Sciences
- The C282Y mutation of the HFE gene is not found in Chinese haemochromatotic patients: multicentre retrospective study.Wilson M. S. Tsui, Lam Pw, Lee Kc, Ma Kf, Chan Yk, Wong Mw, Shea Ping Yip, Wong Cs, Chow As, S T Lo · 2000 · PubMed
- The prevalence of HFE C282Y gene mutation is increased in Spanish patients with porphyria cutanea tarda without hepatitis C virus infectionAgustí Toll, Raquel Celis, MD Ozalla, Miguel Bruguera, Carmen Herrero, M.G. Ercilla · 2006 · Journal of the European Academy of Dermatology and Venereology
- The relevance of the intestinal crypt and enterocyte in regulating iron absorptionPhillip S. Oates · 2007 · Pflügers Archiv - European Journal of Physiology
- Cloning, sequencing and characterization of the rat hereditary hemochromatosis promoter: comparison of the human, mouse and rat HFE promoter regionsMayka Sánchez, Rosa Queralt, Miquel Bruguera, Joan Rodés, Rafael Oliva · 1998 · Gene
- Expression of SFT (Stimulator of Fe Transport) Is Enhanced by Iron Chelation in HeLa Cells and by Hemochromatosis in LiverJianming Yu, Zhong Kang Yu, Marianne Wessling‐Resnick · 1998 · Journal of Biological Chemistry
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- Individuals Homozygous for the H63D Mutation Have Significantly Elevated Iron IndexesJason Samarasena, Wendy Winsor, Richard Lush, Peter Raymond Duggan, Ya‐Gang Xie, Mark Ram Borgaonkar · 2006 · Digestive Diseases and Sciences
- What’s new in hemochromatosisPeter Gochee, Lawrie W. Powell · 2001 · Current Opinion in Hematology
- Alternate splice variants of the hemochromatosis gene HfeDavid A. Rhodes, John Trowsdale · 1999 · Immunogenetics
- Rheumatologic manifestations of gastrointestinal disordersJürgen Braun, Joachim Sieper · 1999 · Current Opinion in Rheumatology
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- In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis miceAlice Rovai, Bomee Chung, Qingluan Hu, Sebastian Hook, Qinggong Yuan, Tibor Kempf, Florian Schmidt, Dirk Grimm, Steven Roger Talbot, Lars Steinbrück et al. · 2022 · Nature Communications
- Structural basis of urea-induced unfolding: Unraveling the folding pathway of hemochromatosis factor EParvez Κhan, Amresh Prakash, Md. Anzarul Haque, Asimul Islam, Md. Imtaiyaz Hassan, Faizan Ahmad · 2016 · International Journal of Biological Macromolecules
- Iron proteins of duodenal enterocytes isolated from mice with genetically and experimentally altered iron metabolismDavid J. Pountney, Abraham M. Konijn, Andrew Tristan McKie, T. J. Peters, K.B. Raja, J R Salisbury, Robert James Simpson · 1999 · British Journal of Haematology
- Hereditary Hemochromatosis: Genetics, Pathogenesis, and Clinical ManagementJacob Alexander, Kris V. Kowdley · 2005 · Annals of Hepatology
- Defective trafficking and localization of mutated transferrin receptor 2: implications for type 3 hereditary hemochromatosisDaniel F. Wallace, Lesa Summerville, Emily M. Crampton, V. Nathan Subramaniam · 2007 · American Journal of Physiology-Cell Physiology
- Molecular regulation of hepatic expression of iron regulatory hormone hepcidinPhillip S. Oates, Umbreen Ahmed · 2007 · Journal of Gastroenterology and Hepatology
- Transferrin receptor activity and localisation in the rat duodenumPhillip S. Oates, Carla Thomas, Evan Huxley Morgan · 2000 · Pflügers Archiv - European Journal of Physiology
- The haemochromatosis gene: A global perspective and implications for the Asia–Pacific regionMarianne Mortimore, Alison T. Merryweather‐Clarke, Kathryn Robson, Lawrie W. Powell · 1999 · Journal of Gastroenterology and Hepatology
- Iron metabolism in insect disease vectors: Mining the Anopheles gambiae translated protein databaseJoy J. Winzerling, Daphne Q.‐D. Pham · 2006 · Insect Biochemistry and Molecular Biology
- Stoichiometries of transferrin receptors 1 and 2 in human liverMaja Chloupková, An-Sheng Zhang, Caroline A. Enns · 2009 · Blood Cells Molecules and Diseases
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- BPDE induces human trophoblast cell ferroptosis by up-regulating iron metabolism and promoting GPX4 proteasomal degradationPeng Tian, Zhongyan Xu, Jiarong Guo, Jingsong Zhao, Rong Wang, Weina Chen, Yang Yang, Wenxin Huang, Chenyang Mi, Huidong Zhang · 2021 · Ecotoxicology and Environmental Safety
- Differential HFE Gene Expression Is Regulated by Alternative Splicing in Human TissuesRute Martins, Bruno Dias Rodrigues Silva, Daniela Proença, Paula Faustino · 2011 · PLoS ONE
- Precipitation of iron overload and hereditary hemochromatosis after successful treatment of celiac diseaseMichael A. Heneghan, Kenneth M Feeley, Fiona M. Stevens, M. P. G. Little, Ciaran F. McCarthy · 2000 · The American Journal of Gastroenterology
- A role for sex and a common HFE gene variant in brain iron uptakeKari A. Duck, Elizabeth B. Neely, Ian A. Simpson, James R. Connor · 2017 · Journal of Cerebral Blood Flow & Metabolism
- Expression of the HFE allelic variant H63D in SH-SY5Y cells affects tau phosphorylation at serine residuesEric C. Hall, Sang Yong Lee, Nootchanat Mairuae, Zachary Simmons, James R. Connor · 2009 · Neurobiology of Aging
- Identification of 96 single nucleotide polymorphisms in eight genes involved in iron metabolism: efficiency of bioinformatic extraction compared with a systematic sequencing approachVéronique Douabin-Gicquel, Nicolas Soriano, Hélène Ferran, F Wojcik, Elisabeth Palierne, Sara Tamim, Thomas Jovelin, Andrew Tristan McKie, Jean‐Yves Le Gall, Véronique David et al. · 2001 · Human Genetics
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- Analysis of the HFE gene (C282Y, H63D and S65C) mutations in a general Chinese Han populationAifen Lin, W. H. Yan, Heping Xu, M. Zhu, Mengya Zhou · 2007 · Tissue Antigens
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