The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor α and estrogen receptor β
Open accessAbstract
The molecular mechanism used by environmental chemicals to exert their hormone-like actions is still only partially resolved. Although it generally is accepted that xenoestrogens act at the genomic level by binding to intracellular estrogen receptors, we have shown here that they trigger nongenomic effects in pancreatic β cells. Both xenoestrogens and the circulating hormone, 17β-estradiol, bind with high affinity to a common membrane binding site unrelated to the intracellular estrogen receptors ERα and ERβ. This binding site is shared by dopamine, epinephrine, and norepinephrine and has the pharmacological profile of the γadrenergic receptor. This study provides an outline of the membrane receptor involved in rapid xenoestrogen actions.
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Quesada, I., Nadal, A., & Soria, B. (1999) · Diabetes · doi:10.2337/diabetes.48.12.2390 · Cited by 99
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Cited by
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
Vandenberg, L. N., Colborn, T., Hayes, T. B., Heindel, J. J., Jacobs, D. R., Lee, D.-H., Shioda, T., Soto, A. M., vom Saal, F. S., Welshons, W. V., et al. (2012) · Endocrine Reviews · doi:10.1210/er.2011-1050 · Cited by 3,209
EDC-2: the endocrine society's second scientific statement on endocrine-disrupting chemicals
Gore, A. C., Chappell, V. A., Fenton, S. E., Flaws, J. A., Nadal, A., Prins, G. S., Toppari, J., & Zoeller, R. T. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1010 · Cited by 2,407
Metabolism disrupting chemicals and metabolic disorders
Heindel, J. J., Blumberg, B., Cave, M., Machtinger, R., Mantovani, A., Mendez, M. A., Nadal, A., Palanza, P., Panzica, G., Sargis, R., et al. (2017) · Reproductive Toxicology · doi:10.1016/j.reprotox.2016.10.001 · Cited by 1,101
Self-citationThe neurobiology and control of anxious states
Millan, M. J. (2003) · Progress in Neurobiology · doi:10.1016/s0301-0082(03)00087-x · Cited by 965
In vitro molecular mechanisms of bisphenol A action.
Wetherill, Y. B., Akingbemi, B. T., Kanno, J., McLachlan, J. A., Nadal, A., Sonnenschein, C., Watson, C. S., Zoeller, R. T., & Belcher, S. M. (2007) · Reproductive Toxicology · doi:10.1016/j.reprotox.2007.05.010 · Cited by 920
Metadata
- Authors
- Nadal, A., Ropero, A. B., Laribi, O., Maillet, M., Fuentes, E., & Soria, B.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2000-10-10
- Volume
- 97
- Issue
- 21
- Pages
- 11603-11608
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1985941840
- Cited by
- 372
- References
- 1
- FWCI
- 10.95
- Type
- journal article
- Language
- en
- Open access
- green
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- Nadal, A., Ropero, A. B., Laribi, O., Maillet, M., Fuentes, E., & Soria, B. (2000). Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor α and estrogen receptor β. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.97.21.11603
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