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Cited by 292

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

CD39 Is an Ecto-(Ca2+,Mg2+)-apyrase

Open access
Wang, Ting-Fang, Guidotti, Guido·1996·Journal of Biological Chemistry

Abstract

CD39, a 70- to 100-kDa molecule expressed primarily on activated lymphoid cells, was previously identified as a surface marker of Epstein Barr virus (EBV)-transformed B cells. In this report, we show that an ecto-(Ca2+,Mg2+)-apyrase activity is present on EBV-transformed B cells, but not on B or T lymphomas. The coincidence between CD39 expression and ecto-apyrase activity on immune cells suggests that CD39 may be an ecto-apyrase. This supposition is supported by the observation that the amino acid sequence of CD39 is significantly homologous to those of several newly identified nucleotide triphosphatases. Finally, we show that CD39 indeed has ecto-apyrase activity by expression in COS-7 cells.

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Metadata

Authors
Wang, T.-F., & Guidotti, G.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
1996-04
Volume
271
Issue
17
Pages
9898-9901
ISSN
0021-9258 (ISSN-L)
OpenAlex
W1492226152
Cited by
292
References
25
FWCI
11.45
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: CD39 Is an Ecto-(Ca2+,Mg2+)-apyrase. https://app.cochat.ai/papers/10.1074/jbc.271.17.9898
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Wang, T.-F., & Guidotti, G. (1996). CD39 Is an Ecto-(Ca2+,Mg2+)-apyrase. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.271.17.9898

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.