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Na+/H+ Exchangers of Mammalian Cells
Open accessAbstract
Ejection of intracellular H+ in exchange for external Na+ is the most effective means of eliminating excess acid from actively metabolizing cells. Na+/H+ exchange is also crucial for the regulation of the cellular volume and for the reabsorption of NaCl across renal, intestinal, and other epithelia. This remarkable array of essential functions is carried out by a family of antiporters, known generically as Na+/H+ exchangers (NHEs).1 These are highly regulated (glyco)phosphoproteins present in virtually all mammalian tissues and species studied to date.
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Cited by
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An overview of inhibitors of Na+/H+ exchanger
Masereel, B. (2003) · European Journal of Medicinal Chemistry · doi:10.1016/s0223-5234(03)00100-4 · Cited by 441
Physiological mechanisms underlying OsNAC5-dependent tolerance of rice plants to abiotic stress
Song, S.-Y., Chen, Y., Chen, J., Dai, X.-Y., & Zhang, W.-H. (2011) · Planta · doi:10.1007/s00425-011-1403-2 · Cited by 367
Mitochondrial potassium transport: the K+ cycle
Garlid, K. D., & Paucek, P. (2003) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(03)00108-7 · Cited by 365
Metadata
- Authors
- Orlowski, J., & Grinstein, S.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1997-09
- Volume
- 272
- Issue
- 36
- Pages
- 22373-22376
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2081230957
- Cited by
- 575
- References
- 0
- FWCI
- 13.84
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
