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The Molecular Basis for the Absence ofN-Glycolylneuraminic Acid in Humans
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In humans, GGTA1 and CMAH evolved into pseudogenes and the α-Gal and the Neu5Gc epitopes are not expressed.
“In humans, GGTA1 (ref. 18) and CMAH19 evolved into pseudogenes and the α-Gal and the Neu5Gc epitopes are not expressed (Fig. 1a).”
From Design and testing of a humanized porcine donor for xenotransplantation (2023) · cites this paper as [19]
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Metadata
- Authors
- Irie, A., Koyama, S., Kozutsumi, Y., Kawasaki, T., & Suzuki, A.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1998-06
- Volume
- 273
- Issue
- 25
- Pages
- 15866-15871
- ISSN
- 0021-9258
- Cited by
- 371
- References
- 0
- Language
- en
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