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G Protein-coupled Receptors
Open accessAbstract
Nearly 2000 G protein-coupled receptors (GPCRs)1 have been reported since bovine opsin was cloned in 1983 (1) and the β-adrenergic receptor in 1986 (2). They are classified into over 100 subfamilies according to the sequence homology, ligand structure, and receptor function. A substantial degree of amino acid homology is found among members of a particular subfamily, but comparisons between subfamilies show significantly less or no similarity.
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Cited by
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Fredholm, B. B., IJzerman, A. P., Jacobson, K. A., Klotz, K.-N., & Linden, J. (2001) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01511-4 · Cited by 2,585
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Metadata
- Authors
- Ji, T. H., Grossmann, M., & Ji, I.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1998-07
- Volume
- 273
- Issue
- 28
- Pages
- 17299-17302
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2033388874
- Cited by
- 1,277
- References
- 0
- FWCI
- 34.55
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Ji, T. H., Grossmann, M., & Ji, I. (1998). G Protein-coupled Receptors. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.273.28.17299
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
