The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Identification of a Human Histone Acetyltransferase Related to Monocytic Leukemia Zinc Finger Protein
Open accessAbstract
We describe here the identification and functional characterization of a novel human histone acetyltransferase, termed MORF (monocytic leukemia zinc finger protein-related factor). MORF is a 1781-residue protein displaying significant sequence similarity to MOZ (monocytic leukemia zinc finger protein). MORF is ubiquitously expressed in adult human tissues, and its gene is located at human chromosome band 10q22. MORF has intrinsic histone acetyltransferase activity. In addition to its histone acetyltransferase domain, MORF possesses a strong transcriptional repression domain at its N terminus and a highly potent activation domain at its C terminus. Therefore, MORF is a novel histone acetyltransferase that contains multiple functional domains and may be involved in both positive and negative regulation of transcription.
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Cites
Histone acetylation in chromatin structure and transcription
Grunstein, M. (1997) · Nature · doi:10.1038/38664 · Cited by 2,884
Histone acetylation and transcriptional regulatory mechanisms
Struhl, K. (1998) · Genes & Development · doi:10.1101/gad.12.5.599 · Cited by 1,815
Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex
Tong, J. K., Hassig, C. A., Schnitzler, G. R., Kingston, R. E., & Schreiber, S. L. (1998) · Nature · doi:10.1038/27699 · Cited by 692
Cited by
Tong, J. J. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.5.1114 · Cited by 181
Metadata
- Authors
- Champagne, N., Bertos, N. R., Pelletier, N., Wang, A. H., Vezmar, M., Yang, Y., Heng, H. H., & Yang, X.-J.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1999-10
- Volume
- 274
- Issue
- 40
- Pages
- 28528-28536
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1986648879
- Cited by
- 168
- References
- 3
- FWCI
- 3.26
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- The paper
- Champagne, N., Bertos, N. R., Pelletier, N., Wang, A. H., Vezmar, M., Yang, Y., Heng, H. H., & Yang, X.-J. (1999). Identification of a Human Histone Acetyltransferase Related to Monocytic Leukemia Zinc Finger Protein. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.274.40.28528
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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