The Yeast Frataxin Homologue Mediates Mitochondrial Iron Efflux

Radisky, Derek C., Babcock, Michael C., Kaplan, Jerry·1999·Journal of Biological Chemistry

Cited by (277)

Items 101–200 of 277

  1. Recent advances in disorders of iron metabolism: mutations, mechanisms and modifiers
    C. N. Roy · 2001 · Human Molecular Genetics
  2. Mitochondrial pathophysiology in Friedreich's ataxia
    Pilar González‐Cabo, Francesc Palau · 2013 · Journal of Neurochemistry
  3. Yeast as a model for studying human neurodegenerative disorders
    Leonor Miller‐Fleming, Flaviano Giorgini, Tiago F. Outeiro · 2008 · Biotechnology Journal
  4. MDL1 is a High Copy Suppressor of ATM1: Evidence for a Role in Resistance to Oxidative Stress
    Maja Chloupková, Linda S. LeBard, David M. Koeller · 2003 · Journal of Molecular Biology
  5. Yeast Lacking Cu-Zn Superoxide Dismutase Show Altered Iron Homeostasis
    Jeane M. De Freitas, Amir Liba, Rogério Meneghini, Joan Selverstone Valentine, Edith Butler Gralla · 2000 · Journal of Biological Chemistry
  6. Development of potential iron chelators for the treatment of Friedreich’s ataxia: ligands that mobilize mitochondrial iron
    Des Raymond Richardson, C. Mouralian, Prem Ponka, E. Becker · 2001 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  7. Neurological effects of recombinant human erythropoietin in Friedreich's ataxia: A clinical pilot trial
    Sylvia Boesch, Brigitte Sturm, Sascha Hering, Barbara Scheiber‐Mojdehkar, Hannes Steinkellner, Hans Goldenberg, Werner H Poewe · 2008 · Movement Disorders
  8. Insights into the role of oxidative stress in the pathology of Friedreich ataxia using peroxidation resistant polyunsaturated fatty acids
    Maria Grazia Cotticelli, Andrew M. Crabbe, Robert B. Wilson, Mikhail S. Shchepinov · 2013 · Redox Biology
  9. The Ferroxidase Activity of Yeast Frataxin
    Park, Sungjo, Gakh, Oleksandr, Mooney, Steven M., Isaya, Grazia · 2002 · Journal of Biological Chemistry
  10. Deferiprone for the treatment of Friedreich's ataxia
    Massimo Pandolfo, Laura Hausmann · 2013 · Journal of Neurochemistry
  11. Cytopathies involving mitochondrial complex II
    Ackrell, Brian A.C · 2002 · Molecular Aspects of Medicine
  12. The mitochondrial protein frataxin prevents nuclear damage
    Gopalakrishnan Karthikeyan · 2002 · Human Molecular Genetics
  13. The genetics of inherited sideroblastic anemias
    Mark D. Fleming · 2002 · Seminars in Hematology
  14. Molecular Mechanisms and Regulation of Iron Transport
    Jayong Chung, Marianne Wessling‐Resnick · 2003 · Critical Reviews in Clinical Laboratory Sciences
  15. Role of the Mitochondrial Hsp70s, Ssc1 and Ssq1, in the Maturation of Yfh1
    Cindy Voisine, Brenda A. Schilke, Maikke B. Ohlson, Helmut Beinert, Jarosław Marszałek, Elizabeth Anne Craig · 2000 · Molecular and Cellular Biology
  16. Inhibition of Heme Biosynthesis Prevents Transcription of Iron Uptake Genes in Yeast
    Robert Crisp, Annette M. Pollington, Charles A. Galea, Shulamit Jaron, Yuko Yamaguchi‐Iwai, Jerry Kaplan · 2003 · Journal of Biological Chemistry
  17. Rescue of the Friedreich's ataxia knockout mouse by human YAC transgenesis
    Mark A. Pook, Sahar Al‐Mahdawi, Christopher J. Carroll, Mireille Cossée, Hélène M. Puccio, Lorraine Lawrence, Peter A. Clark, M.B. Lowrie, J. L. Bradley, Mark J. Cooper et al. · 2001 · Neurogenetics
  18. Friedreich ataxia
    Massimo Pandolfo · 2003 · Seminars in Pediatric Neurology
  19. Frataxin deficiency enhances apoptosis in cells differentiating into neuroectoderm
    Manuela M. Santos · 2001 · Human Molecular Genetics
  20. Knock‐out of the cyaY gene in Escherichia coli does not affect cellular iron content and sensitivity to oxidants
    Dong Sheng Li, Keiichi Ohshima, Sarn Jiralerspong, Michel Wieslaw Bojanowski, Massimo Pandolfo · 1999 · FEBS Letters
  21. CCC1 Suppresses Mitochondrial Damage in the Yeast Model of Friedreich's Ataxia by Limiting Mitochondrial Iron Accumulation
    Opal S. Chen, Jerry Kaplan · 2000 · Journal of Biological Chemistry
  22. Genetic and Biochemical Analysis of High Iron Toxicity in Yeast
    Huilan Lin, Liangtao Li, Xuan Jia, Diane M. Ward, Jerry Kaplan · 2010 · Journal of Biological Chemistry
  23. Genetic Disorders Affecting Proteins of Iron Metabolism: Clinical Implications
    Sujit Sheth, Gary M. Brittenham · 2000 · Annual Review of Medicine
  24. Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization
    E. Becker, Judith M. Greer, Prem Ponka, Des Raymond Richardson · 2002 · Blood
  25. Metal ion transport in eukaryotic microorganisms: insights from Saccharomyces cerevisiae
    David J. Eide · 2000 · Advances in microbial physiology/Advances in Microbial Physiology
  26. Frataxin: its role in iron metabolism and the pathogenesis of Friedreich's ataxia
    Becker, Erika, Richardson, Des R. · 2001 · The International Journal of Biochemistry & Cell Biology
  27. Friedreich?s ataxia: iron chelators that target the mitochondrion as a therapeutic strategy?
    Des Raymond Richardson · 2003 · Expert Opinion on Investigational Drugs
  28. Iron Transport and Signaling in Plants
    Sébastien Thomine, Viviane Lanquar · 2010 · Signaling and communication in plants
  29. Drosophila Frataxin: An Iron Chaperone during Cellular Fe−S Cluster Bioassembly
    Kalyan C. Kondapalli, Nicole M. Kok, Andrew Dancis, Timothy L. Stemmler · 2008 · Biochemistry
  30. Friedreich ataxia?update on pathogenesis and possible therapies
    Max Voncken, Panos A. Ioannou, Martin Bruce Delatycki · 2004 · Neurogenetics
  31. THE MOLECULAR BASIS
    Massimo Pandolfo · 2002
  32. Upregulation of expression from the FRDA genomic locus for the therapy of Friedreich ataxia
    Joseph P. Sarsero, Lingli Li, Hady Wardan, Karin Sitte, Robert Williamson, Panos A. Ioannou · 2002 · The Journal of Gene Medicine
  33. Iron Metabolism and Mitochondrial Abnormalities in Friedreich Ataxia
    Massimo Pandolfo · 2002 · Blood Cells Molecules and Diseases
  34. Antioxidant enzymes in blood of patients with Friedreich's ataxia
    Giulia Tozzi · 2002 · Archives of Disease in Childhood
  35. Understanding the binding properties of an unusual metal‐binding protein − a study of bacterial frataxin
    Chiara Pastore, M. Franzese, Filomena Sica, Pierandrea Temussi, Annalisa Pastore · 2007 · FEBS Journal
  36. Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial iron homeostasis in Saccharomyces cerevisiae
    Steven S. Branda · 1999 · Human Molecular Genetics
  37. EPR and Mössbauer Spectroscopy of Intact Mitochondria Isolated from Yah1p-DepletedSaccharomyces cerevisiae
    Ren Miao, Marlène Martinho, Jessica Garber Morales, Hansoo Kim, E. Ann Ellis, Roland Lill, Michael P. Hendrich, Eckard Münck, Paul A. Lindahl · 2008 · Biochemistry
  38. A Role for Iron-Sulfur Clusters in the Regulation of Transcription Factor Yap5-dependent High Iron Transcriptional Responses in Yeast
    Liangtao Li, Ren Miao, Sophie Bertram, Xuan Jia, Diane M. Ward, Jerry Kaplan · 2012 · Journal of Biological Chemistry
  39. Drug Insight: antioxidant therapy in inherited ataxias
    Massimo Pandolfo · 2008 · Nature Clinical Practice Neurology
  40. Iron Dysregulation in Friedreich Ataxia
    Robert B. Wilson · 2006 · Seminars in Pediatric Neurology
  41. The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich’s ataxia
    Des Raymond Richardson, Michael L.H. Huang, Megan Whitnall, E. Becker, Prem Ponka, Yohan Suryo Rahmanto · 2009 · Journal of Molecular Medicine
  42. Biogenesis of iron–sulfur proteins in eukaryotes: components, mechanism and pathology
    Jana Gerber, Roland Lill · 2002 · Mitochondrion
  43. The Molecular Basis of Friedreich Ataxia
    Massimo Pandolfo · 2002 · Advances in experimental medicine and biology
  44. Rare causes of hereditary iron overload
    Prem Ponka · 2002 · Seminars in Hematology
  45. An association between migraine and cutaneous allodynia
    Rami Burstein, David Yarnitsky, Itay Goor‐Aryeh, Bernard J. Ransil, Zahid H. Bajwa · 2000 · Annals of Neurology
  46. Genetic analysis of iron citrate toxicity in yeast: Implications for mammalian iron homeostasis
    Opal S. Chen, Shawn Hemenway, Jerry Kaplan · 2002 · Proceedings of the National Academy of Sciences
  47. Molecular basis of Friedreich ataxia
    Massimo Pandolfo · 2001 · Movement Disorders
  48. The mitochondrial protein frataxin is essential for heme biosynthesis in plants
    María Victoria Maliandi, María V. Busi, Valeria R. Turowski, Laura Leaden, Alejandro Araya, Diego F. Gomez‐Casati · 2010 · FEBS Journal
  49. Pathophysiology of mitochondrial cell death control
    Helena L.A. Vieira, Guido Kroemer · 1999 · Cellular and Molecular Life Sciences
  50. Maturation of Frataxin Within Mammalian and Yeast Mitochondria: One-Step Processing by Matrix Processing Peptidase
    Gordon, D. M., Shi, Q., Dancis, A., Pain, D. · 1999 · Human Molecular Genetics
  51. Bacterial IscU is a well folded and functional single domain protein
    Salvatore Adinolfi, Francesca Maria Rizzo, Laura Masino, Margie M. Nair, Stephen R. Martin, Annalisa Pastore, Piero Andrea Temussi · 2004 · European Journal of Biochemistry
  52. Friedreich Ataxia: Detection of GAA Repeat Expansions and Frataxin Point Mutations
    Massimo Pandolfo · 2006 · Humana Press eBooks
  53. Yeast models of human mitochondrial diseases: from molecular mechanisms to drug screening
    Christine Schwimmer, Malgorzata Rak, Linnka Lefebvre‐Legendre, Stéphane Duvezin‐Caubet, Guillaume Plane, Jean‐Paul di Rago · 2006 · Biotechnology Journal
  54. Frataxin interacts with Isu1 through a conserved tryptophan in its β-sheet
    Sébastien Leidgens, Sébastien De Smet, Françoise Foury · 2009 · Human Molecular Genetics
  55. Movement disorders in Friedreich's ataxia
    Jyhgong Gabriel Hou, Joseph J. Jankovic · 2002 · Journal of the Neurological Sciences
  56. The therapeutic potential of iron chelators
    Des Raymond Richardson · 1999 · Expert Opinion on Investigational Drugs
  57. Mitochondrial Iron Metabolism in the Yeast Saccharomyces cerevisiae
    Elizabeth Anne Craig, Cindy Voisine, Brenda A. Schilke · 1999 · Biological Chemistry
  58. X-ray fluorescence imaging reveals subcellular biometal disturbances in a childhood neurodegenerative disorder
    Alexandra Grubman, Simon James, Janine L. James, C. Duncan, Irene Volitakis, James L. Hickey, Peter John Crouch, Paul S. Donnelly, Katja M. Kanninen, Jeffrey R. Liddell et al. · 2014 · Chemical Science
  59. Idebenone in Friedreich's ataxia
    Caterina Tonon, Raffaele Lodi · 2008 · Expert Opinion on Pharmacotherapy
  60. Iron–Sulphur Clusters, Their Biosynthesis, and Biological Functions in Protozoan Parasites
    Vahab Ali, Tomoyoshi Nozaki · 2013 · Advances in Parasitology/Advances in parasitology
  61. Blood-Feeding Induces Reversible Functional Changes in Flight Muscle Mitochondria of Aedes aegypti Mosquito
    Renata L.S. Goncalves, Ana Carolina L. Machado, Gabriela O. Paiva‐Silva, Marcos Henrique Ferreira Sorgine, Marisa M. Momoli, José Henrique M. Oliveira, Marcos André Vannier-Santos, Antônio Galina, José Henrique M. Oliveira, Marcus Fernandes de Oliveira · 2009 · PLoS ONE
  62. Frataxin deficiency and mitochondrial dysfunction
    Massimo Pandolfo · 2002 · Mitochondrion
  63. Distinct roles for two N-terminal cleaved domains in mitochondrial import of the yeast frataxin homolog, Yfh1p
    D. M. Gordon · 2001 · Human Molecular Genetics
  64. Recent advances in degenerative ataxias
    Thomas Klockgether · 2000 · Current Opinion in Neurology
  65. Tangled web of interactions among proteins involved in iron–sulfur cluster assembly as unraveled by NMR, SAXS, chemical crosslinking, and functional studies
    Jin Hae Kim, Jameson R. Bothe, T. Reid Alderson, John L. Markley · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  66. Functional studies of frataxin
    Grazia Isaya, HA O'Neill, Oleksandr Gakh, S Park, R Mantcheva, SM Mooney · 2004 · Acta Paediatrica
  67. Friedreich’s ataxia is a mitochondrial disorder
    Jerry Kaplan · 1999 · Proceedings of the National Academy of Sciences
  68. The role of the mitochondrion in cellular iron homeostasis
    Nichole D Schueck, Michael Woontner, David M. Koeller · 2001 · Mitochondrion
  69. Mitochondrial biology and dysfunction in secondary mitochondrial disease
    Megan J. Baker, Jordan J. Crameri, David R. Thorburn, Ann E. Frazier, Diana Stojanovski · 2022 · Open Biology
  70. Increased IRP1 activity in Friedreich ataxia
    Lioba Lobmayr, David G. Brooks, Robert B. Wilson · 2005 · Gene
  71. Therapeutic Developments in Friedreich Ataxia
    Robert B. Wilson · 2012 · Journal of Child Neurology
  72. Mitochondrial metals as a potential therapeutic target in neurodegeneration
    Alexandra Grubman, Anthony Robert White, Jeffrey R. Liddell · 2013 · British Journal of Pharmacology
  73. Frataxin and frataxin deficiency in Friedreich's ataxia
    Wilson, Robert B · 2003 · Journal of the Neurological Sciences
  74. Altered sterol metabolism in budding yeast affects mitochondrial iron-sulfur (Fe-S) cluster synthesis
    Ward, Diane M., Chen, Opal S., Li, Liangtao, Kaplan, Jerry, Bhuiyan, Shah Alam, Natarajan, Selvamuthu K., Bard, Martin, Cox, James E. · 2018 · Journal of Biological Chemistry
  75. Sequence and Analysis of Chromosome I of the Amitochondriate Intracellular Parasite Encephalitozoon cuniculi (Microspora)
    Pierre Peyret, Michaël Doron Katinka, Simone Duprat, Francis Duffieux, Valérie Barbe, Martin Barbazanges, Jean Weissenbach, William Saurin, Christian P. Vivarès · 2001 · Genome Research
  76. Expression of the human ferritin light chain in a frataxin mutant yeast affects ageing and cell death
    Desmyter, Liesbeth, Dewaele, Sylviane, Reekmans, Rieka, Nystrom, Thomas, Contreras, Roland, Chen, Cuiying · 2004 · Experimental Gerontology
  77. Zinc suppresses the iron-accumulation phenotype of Saccharomyces cerevisiae lacking the yeast frataxin homologue (Yfh1)
    Renata Santos, Andrew Dancis, David J. Eide, Jean‐Michel Camadro, Emmanuel Lesuisse · 2003 · Biochemical Journal
  78. Mitochondrial Dysfunction in Friedreich's Ataxia: From Pathogenesis to Treatment Perspectives
    Raffaele Lodi, B. Rajagopalan, J. L. Bradley, D.J. Taylor, Jenifer G. Crilley, Paul E. Hart, Andrew Matthew Blamire, David Neil Manners, Peter Styles, Anthony H.V. Schapira et al. · 2002 · Free Radical Research
  79. Frataxin overexpressing mice
    Miranda, Carlos J, Santos, Manuela M, Ohshima, Keiichi, Tessaro, Marco, Sequeiros, Jorge, Pandolfo, Massimo · 2004 · FEBS Letters
  80. Reduced Bone Mineral Density in SOCS-2-Deficient Mice
    Mattias Lorentzon, Chris J Greenhalgh, Subburaman Mohan, Warren S. Alexander, Claes Ohlsson · 2004 · Pediatric Research
  81. Mmf1p Couples Amino Acid Metabolism to Mitochondrial DNA Maintenance in Saccharomyces cerevisiae
    Dustin C. Ernst, Diana M. Downs · 2018 · mBio
  82. Friedreich's ataxia and iron metabolism
    Neil S. Gordon · 2000 · Brain and Development
  83. Iron metabolism in mammalian cells
    Brandie Walker, Jacqueline Tiong, Wilfred Arthur Jefferies · 2001 · International review of cytology
  84. Intestinal metal ion absorption: an update
    Andreas Rolfs, Matthias A. Hediger · 2001 · Current Opinion in Gastroenterology
  85. Friedreich ataxia
    Massimo Pandolfo · 2011 · Handbook of clinical neurology
  86. Friedreich Ataxia
    Massimo Pandolfo · 2012 · Journal of Child Neurology
  87. Spinocerebellar ataxias due to mitochondrial defects
    Jerry Kaplan · 2002 · Neurochemistry International
  88. Identification of three novel frameshift mutations in patients with Friedreich's ataxia
    Mark A. Pook, SAHAR A H AL-MAHDAWI, NEIL H THOMAS, RICHARD APPLETON, ANDREW NORMAN, R. Mountford, SUSAN CHAMBERLAIN · 2000 · Journal of Medical Genetics
  89. Biochemistry of cardiomyopathy in the mitochondrial disease Friedreich's ataxia
    Darius J.R. Lane, Michael L.H. Huang, Samantha Ting, Sutharshani Sivagurunathan, Des Raymond Richardson · 2013 · Biochemical Journal
  90. Impact of Drosophila Models in the Study and Treatment of Friedreich’s Ataxia
    Véronique Monnier, José Vicente Llorens, Juan A. Navarro · 2018 · International Journal of Molecular Sciences
  91. Role of Mitochondrial Carrier Protein Mrs3/4 in Iron Acquisition and Oxidative Stress Resistance of Cryptococcus neoformans
    Karin J. Nyhus, Luiz S. Ozaki, Eric S. Jacobson · 2002 · Medical Mycology
  92. Pathophysiology of the Optic Neuropathy Associated With Friedreich Ataxia
    CLARON D. ALLDREDGE · 2003 · Archives of Ophthalmology
  93. Nrf2 activators for the treatment of rare iron overload diseases: From bench to bedside
    Yimin Dong, Meng Zheng, Weizhong Ding, Hanfeng Guan, Jun Xiao, Feng Li · 2025 · Redox Biology
  94. Cardiac transplantation: A temporary solution for Friedreich’s ataxia-induced dilated cardiomyopathy
    Tara Sedlak, Mann Chandavimol, Lynn Straatman · 2004 · The Journal of Heart and Lung Transplantation
  95. Iron uncouples oxidative phosphorylation in brain mitochondria isolated from vitamin E-deficient rats
    Govind T. Vatassery, Eugene G. DeMaster, James C. K. Lai, William E. Smith, Hung T. Quach · 2004 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  96. Fragile X syndrome and Friedreich’s ataxia: two different paradigms for repeat induced transcript insufficiency
    Ed Grabczyk, Daman Kumari, Karen Usdin · 2001 · Brain Research Bulletin
  97. Aging and Oxidative Stress Response in the CNS
    Vittorio Calabrese, David Allan Butterfield, A. M. Giuffrida Stella · 2008 · Springer eBooks
  98. Primary and Secondary Drug Screening Assays for Friedreich Ataxia
    Maria Grazia Cotticelli, Lynn A. Rasmussen, Nicole L. Kushner, Sara N. McKellip, Melinda Ingrum Sosa, Anna Manouvakhova, Shuang Feng, E. Lucile White, Joseph A. Maddry, Jill Heemskerk et al. · 2011 · SLAS DISCOVERY
  99. Mitochondrial Dysfunction in Friedreich’s Ataxia
    Raffaele Lodi, Doris J. Taylor, Anthony H.V. Schapira · 2001 · Neurosignals
  100. Bioavailable copper and manganese in soils from Iceland and their relationship with scrapie occurrence in sheep
    Kristin Vala Ragnarsdottir, D.P. Hawkins · 2005 · Journal of Geochemical Exploration