Critical Role of WW Domain Phosphorylation in Regulating Phosphoserine Binding Activity and Pin1 Function

Lu, Pei-Jung, Zhou, Xiao Zhen, Liou, Yih-Cherng, Noel, Joseph P., Lu, Kun Ping·2002·Journal of Biological Chemistry

Cited by (248)

Items 101–200 of 248

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  2. Control of Protein−Protein Interactions: Structure-Based Discovery of Low Molecular Weight Inhibitors of the Interactions between Pin1 WW Domain and Phosphopeptides
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  6. Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA
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  7. Pin1 overexpression is associated with poor differentiation and survival in oral squamous cell carcinoma
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  8. Pin1‐Targeted Therapy for Systemic Lupus Erythematosus
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  9. Complete Thermodynamic and Kinetic Characterization of the Isomer-Specific Interaction between Pin1-WW Domain and the Amyloid Precursor Protein Cytoplasmic Tail Phosphorylated at Thr668
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  10. Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis
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  11. Phosphorylation of the N-terminal Domain Regulates Subcellular Localization and DNA Binding Properties of the Peptidyl-prolyl cis/trans Isomerase hPar14
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  12. Pin1 mediates Aβ 42 -induced dendritic spine loss
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  13. Peptidyl Prolyl Isomerase PIN1 Directly Binds to and Stabilizes Hypoxia-Inducible Factor-1α
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  14. Pin1–FADD Interactions Regulate Fas-Mediated Apoptosis in Activated Eosinophils
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  15. NMR Structural Studies of the ItchWW3 Domain Reveal that Phosphorylation at T30 Inhibits the Interaction with PPxY-Containing Ligands
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  16. Development of Pin1 Inhibitors and their Potential as Therapeutic Agents
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  17. PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation
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  18. Compound mutations in human anion exchanger 1 are associated with complete distal renal tubular acidosis and hereditary spherocytosis
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  19. Molecular Mechanism of Pin1–Tau Recognition and Catalysis
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  20. The Prolyl Isomerase Pin1 Controls Lipopolysaccharide-Induced Priming of NADPH Oxidase in Human Neutrophils
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  39. Dynamic regulation of Pin1 expression and function during zebrafish development
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  42. Peptidyl‐prolyl cis‐trans isomerase NIMA‐interacting 1 directly binds and stabilizes Nrf2 in breast cancer
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  47. Prolyl Isomerase Pin1 Protects Mice from Endotoxin Shock
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  48. Discovery of indeno[1,2- $$c$$ c ]quinoline derivatives as dual topoisomerases I/II inhibitors: Part 3
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  52. Modulating the Affinities of Phosphopeptides for the Human Pin1 WW Domain Using 4-Substituted Proline Derivatives
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  57. Long-term normalization of calcineurin activity in model mice rescues Pin1 and attenuates Alzheimer’s phenotypes without blocking peripheral T cell IL-2 response
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  59. TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cells
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  60. Multisite phosphorylation of Pin1-associated mitotic phosphoproteins revealed by monoclonal antibodies MPM-2 and CC-3
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  61. Correction: A Dynamic View of Domain-Motif Interactions
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