The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
The Cytochrome bc 1 and Cytochromec Oxidase Complexes Associate to Form a Single Supracomplex in Yeast Mitochondria
Open accessAbstract
The mitochondrial electron transport chain complexes are large multisubunit complexes embedded in the inner membrane. We report here that in the yeast Saccharomyces cerevisiae, the cytochrome bc(1) and cytochrome c oxidase complexes co-exist as a larger complex of approximately 1000 kDa in the mitochondrial membrane. Following solubilization with a mild detergent, the cytochrome bc(1)-cytochrome c oxidase complex remains stable. It was analyzed using the techniques of gel filtration and blue native-polyacrylamide gel electrophoresis. Direct physical association of subunits of the cytochrome bc(1) complex with those of the cytochrome c oxidase complex was verified by co-immunoprecipitation analysis. Our data indicate that the cytochrome bc(1) complex is exclusively in association with the cytochrome c oxidase complex in yeast mitochondria. We term this complex the cytochrome bc(1)-cytochrome c oxidase supracomplex.
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Self-citationPich, S., Bach, D., Briones, P., Liesa, M., Camps, M., Testar, X., Palacín, M., & Zorzano, A. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi149 · Cited by 455
Copper trafficking to the mitochondrion and assembly of copper metalloenzymes
Cobine, P. A., Pierrel, F., & Winge, D. R. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.03.002 · Cited by 317
Friedman, J. R., Mourier, A., Yamada, J., McCaffery, J. M., & Nunnari, J. (2015) · eLife · doi:10.7554/elife.07739 · Cited by 291
Lenaz, G., & Genova, M. L. (2007) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00263.2006 · Cited by 155
Metadata
- Authors
- Cruciat, C.-M., Brunner, S., Baumann, F., Neupert, W., & Stuart, R. A.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2000-06
- Volume
- 275
- Issue
- 24
- Pages
- 18093-18098
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1982753455
- Cited by
- 260
- References
- 29
- FWCI
- 1.80
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Cruciat, C.-M., Brunner, S., Baumann, F., Neupert, W., & Stuart, R. A. (2000). The Cytochrome bc 1 and Cytochromec Oxidase Complexes Associate to Form a Single Supracomplex in Yeast Mitochondria. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.m001901200
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
