Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart

Methods of Enzymatic Analysis

(1975) · Journal of AOAC INTERNATIONAL · doi:10.1093/jaoac/58.5.1085 · Cited by 20,078

Methods of Enzymatic Analysis

(1974) · Elsevier eBooks · doi:10.1016/b978-0-12-091304-6.x5001-0 · Cited by 6,786

Methods of enzymatic analysis

(1985) · International Journal of Biochemistry · doi:10.1016/0020-711x(85)90098-9 · Cited by 3,494

Mitochondrial Transport of Cations: Channels, Exchangers, and Permeability Transition

Bernardi, P. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.4.1127 · Cited by 1,546

Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion

Griffiths, E. J., & Halestrap, A. P. (1995) · Biochemical Journal · doi:10.1042/bj3070093 · Cited by 838

Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle

Palmer, J. W., Tandler, B., & Hoppel, C. L. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75283-1 · Cited by 830

Transient and Long-Lasting Openings of the Mitochondrial Permeability Transition Pore Can Be Monitored Directly in Intact Cells by Changes in Mitochondrial Calcein Fluorescence

Petronilli, V., Miotto, G., Canton, M., Brini, M., Colonna, R., Bernardi, P., & Lisa, F. D. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77239-5 · Cited by 677

Myocardial calcium and magnesium in acute ischemic injury.

Shen, A. C., & Jennings, R. B. (1972) · PubMed · Cited by 629

Protection by Cyclosporin A of Ischemia/Reperfusion-Induced Damage in Isolated Rat Hearts

Griffiths, E. J., & Halestrap, A. P. (1993) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.1993.1162 · Cited by 587

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

Bernardi, P., Broekemeier, K. M., & Pfeiffer, D. R. (1994) · Journal of Bioenergetics and Biomembranes · doi:10.1007/bf00762735 · Cited by 561

Ontogenetic development of cardiac tolerance to oxygen deprivation – possible mechanisms

Ošťádal, B., Ošťádalová, I., Kolář, F., Charvátová, Z., & Netuka, I. (2009) · Physiological Research · doi:10.33549/physiolres.931920 · Cited by 31

Dietary nitrate does not modify blood pressure and cardiac output at rest and during exercise in older adults: a randomised cross-over study

Oggioni, C., Jakovljević, D. G., Klonizakis, M., Ashor, A. W., Ruddock, A. D., Ranchordas, M. K., Williams, E. A., & Siervo, M. (2017) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2017.1328666 · Cited by 33

Cardioprotection by Noble Gases

Pagel, P. S. (2009) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2009.03.016 · Cited by 30

Protective Effects of L-Carnitine on Intestinal Ischemia/Reperfusion Injury in a Rat Model

Yuan, Y. (2011) · Journal of Clinical Medicine Research · doi:10.4021/jocmr540w · Cited by 30

Distinct cardioprotective mechanisms of immediate, early and delayed ischaemic postconditioning

Barsukevich, V. C., Васильевна, Б. М., Sanchez, J., Mrochek, A., Whittle, J., Ackland, G. L., Gourine, A. V., & Gourine, A. V. (2014) · Basic Research in Cardiology · doi:10.1007/s00395-014-0452-7 · Cited by 30

Adrenomedullin limits reperfusion injury in experimental myocardial infarction

Hamid, S. A., & Baxter, G. F. (2005) · Basic Research in Cardiology · doi:10.1007/s00395-005-0538-3 · Cited by 29

Cellular and Mitochondrial NAD Homeostasis in Health and Disease

Waddell, J., Khatoon, R., & Kristián, T. (2023) · Cells · doi:10.3390/cells12091329 · Cited by 33

Failure to protect against myocardial ischemia-reperfusion injury with sevoflurane postconditioning in old rats in vivo

Li, H., Zhou, C., CHEN, D., FANG, N., Yao, Y.-T., & Li, L. (2013) · Acta Anaesthesiologica Scandinavica · doi:10.1111/aas.12156 · Cited by 29

Progressive mitochondrial protein lysine acetylation and heart failure in a model of Friedreich’s ataxia cardiomyopathy

Stram, A. R., Wagner, G. R., Fogler, B. D., Pride, P. M., Hirschey, M. D., & Payne, R. M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0178354 · Cited by 29

Microtubules Sequester Acetylated YAP in the Cytoplasm and Inhibit Heart Regeneration

Liu, S., Deshmukh, V., Meng, F., Wang, Y., Morikawa, Y., Steimle, J. D., Li, G., Wang, J., & Martin, J. F. (2024) · Circulation · doi:10.1161/circulationaha.123.067646 · Cited by 31

Changes in specific lipids regulate BAX‐induced mitochondrial permeability transition

Abundis, E. M., Garcı́a, N., Correa, F., Franco, M., & Zazueta, C. (2007) · FEBS Journal · doi:10.1111/j.1742-4658.2007.06166.x · Cited by 28

Relationship between oxidative stress and mitochondrial function in the post-conditioned heart

Correa, F., Garcı́a, N., Robles, C., Abundis, E. M., & Zazueta, C. (2008) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-008-9186-2 · Cited by 28

Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia

Ge, Z., Ionova, I. A., Vladic, N., Pravdić, D., Hirata, N., Vasquez-Vivar, J. M., Pratt, P. F., Warltier, D. C., Pieper, G. M., & Kersten, J. R. (2011) · Cardiovascular Research · doi:10.1093/cvr/cvr079 · Cited by 28

Pharmacological approaches to reperfusion therapy

Morel, O., Perret, T., Delarche, N., Labeque, J.-N., Jouve, B., Elbaz, M., Piot, C. A., & Ovize, M. (2012) · Cardiovascular Research · doi:10.1093/cvr/cvs114 · Cited by 28

Alda‐1 modulates the kinetic properties of mitochondrial aldehyde dehydrogenase ( ALDH 2)

Belmont-Díaz, J., Yoval‐Sánchez, B., Calleja, L. F., Vázquez, J. P. P., & Rodríguez‐Zavala, J. S. (2016) · FEBS Journal · doi:10.1111/febs.13833 · Cited by 30

Mitochondrial aldehyde dehydrogenase 2 activation and cardioprotection

Gong, D., Zhang, H., & Hu, S. (2012) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2012.03.017 · Cited by 28

Measurement of Mitochondrial ROS Formation

Deshwal, S., Antonucci, S., Kaludercic, N., & Lisa, F. D. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7831-1_24 · Cited by 28

Blood NAD levels are reduced in very old patients hospitalized for heart failure

Breton, M., Costemale-Lacoste, J.-F., Li, Z., Lafuente‐Lafuente, C., Belmin, J., & Mericskay, M. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.111051 · Cited by 26

Clinical outcomes of nicorandil administration in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a systematic review and meta-analysis of randomized controlled trials

Geng, N., Ren, L., Xu, L., Zou, D., & Pang, W. (2021) · BMC Cardiovascular Disorders · doi:10.1186/s12872-021-02301-1 · Cited by 27

Sirtuin3 Dysfunction Is the Key Determinant of Skeletal Muscle Insulin Resistance by Angiotensin II

Macconi, D., Perico, L., Longaretti, L., Morigi, M., Cassis, P., Buelli, S., Perico, N., Remuzzi, G., & Benigni, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127172 · Cited by 26

Comparative Metabolomic Profiling Reveals That Dysregulated Glycolysis Stemming from Lack of Salvage NAD+ Biosynthesis Impairs Reproductive Development in Caenorhabditis elegans

Wang, W., McReynolds, M. R., Goncalves, J. F., Shu, M., Dhondt, I., Braeckman, B. P., Lange, S. E., Kho, K., Detwiler, A. C., Pacella, M. J., et al. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.662916 · Cited by 26

Apoptotic induction mediated p53 mechanism and Caspase-3 activity by novel promising cyanoacrylamide derivatives in breast carcinoma

Mohamed, M. F., Samir, N., Ali, A., Ahmed, N., Ali, Y., Aref, S., Hossam, O., Mohamed, M. S., Abdelmoniem, A. M., & Abdelhamid, I. A. (2017) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2017.05.012 · Cited by 26

Interplay between NAD+ and acetyl‑CoA metabolism in ischemia-induced mitochondrial pathophysiology

Klimova, N., Long, A., Scafidi, S., & Kristián, T. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.09.025 · Cited by 26

Combination of exercise and calorie restriction exerts greater efficacy on cardioprotection than monotherapy in obese-insulin resistant rats through the improvement of cardiac calcium regulation

Palee, S., Minta, W., Mantor, D., Sutham, W., Jaiwongkam, T., Kerdphoo, S., Pratchayasakul, W., Chattipakorn, S. C., & Chattipakorn, N. (2019) · Metabolism · doi:10.1016/j.metabol.2019.02.003 · Cited by 26

Altered Ca2+ homeostasis and impaired mitochondrial function in cardiomyopathy

Kuo, T. H., Zhu, L., Golden, K., Marsh, J. D., Bhattacharya, S. K., & Liu, B.-F. (2002) · Molecular and Cellular Biochemistry · doi:10.1023/a:1019967323419 · Cited by 26

NADH hyperoxidation correlates with enhanced susceptibility of aged rats to hypoxia

Foster, K. A., Margraf, R. R., & Turner, D. A. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.11.006 · Cited by 26

Coenzyme depletion by members of the aerolysin family of pore-forming toxins leads to diminished ATP levels and cell death

Fennessey, C. M., Ivie, S. E., & McClain, M. S. (2012) · Molecular BioSystems · doi:10.1039/c2mb25142f · Cited by 25

Calpain inhibitor (BSF 409425) diminishes ischemia/reperfusion-induced damage of rabbit heart mitochondria

Trumbeckaitė, S., Neuhof, C., Zierz, S., & Gellerich, F. N. (2003) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)01610-6 · Cited by 25

Carvedilol Inhibits the Mitochondrial Permeability Transition by an Antioxidant Mechanism

Oliveira, P. J., Esteves, T. C., Rolo, A. P., Palmeira, C. M., & Moreno, A. J. (2004) · Cardiovascular Toxicology · doi:10.1385/ct:4:1:11 · Cited by 25

Arrhythmogenic and metabolic remodelling of failing human heart

Gloschat, C. R., Koppel, A. C., Aras, K. K., Brennan, J. A., Holzem, K. M., & Efimov, I. R. (2016) · The Journal of Physiology · doi:10.1113/jp271992 · Cited by 23

Targeting mitochondria in the infection strategy of the hepatitis C virus

Quarato, G., Scrima, R., Agriesti, F., Moradpour, D., Capitanio, N., & Piccoli, C. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.06.008 · Cited by 26

Postconditioning signalling in the heart: mechanisms and translatability

Bice, J. S., & Baxter, G. F. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12976 · Cited by 24

Modulation of the matrix redox signaling by mitochondrial Ca2+

Domingo, J. S. (2015) · World Journal of Biological Chemistry · doi:10.4331/wjbc.v6.i4.310 · Cited by 26

Effect of melatonin on oncosis of myocardial cells in the myocardial ischemia/reperfusion injury rat and the role of the mitochondrial permeability transition pore

Liu, L. F., Qian, Z. H., Qin, Q., Shi, M., Zhang, H., Tao, X. M., & Zhu, W. (2015) · Genetics and Molecular Research · doi:10.4238/2015.july.3.24 · Cited by 24

Upregulation of mitochondrial NAD+ levels impairs the clonogenicity of SSEA1+ glioblastoma tumor-initiating cells

Son, M. J., Ryu, J., Kim, J. Y., Kwon, Y., Chung, K., Mun, S. J., & Cho, Y. S. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2017.74 · Cited by 24

Mitochondria: A mirror into cellular dysfunction in heart disease

White, M. Y., Edwards, A. V. G., Cordwell, S. J., & Eyk, J. E. V. (2008) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.200780135 · Cited by 24

Extent of damage in ischemic, nonreperfused, and reperfused myocardium of anesthetized rats

Vetterlein, F., Schrader, C., Volkmann, R., Neckel, M., Ochs, M., Schmidt, G., & Hellige, G. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00269.2002 · Cited by 24

Collagen VI myopathies: From the animal model to the clinical trial

Maraldi, N. M., Sabatelli, P., Columbaro, M., Zamparelli, A., Manzoli, F. A., Bernardi, P., Bonaldo, P., & Merlini, L. (2009) · Advances in Enzyme Regulation · doi:10.1016/j.advenzreg.2008.12.009 · Cited by 23

Effects of FK506 and cyclosporin a on calcium ionophore‐induced mitochondrial depolarization and cytosolic calcium in astrocytes and neurons

Kahraman, S., Bambrick, L. L., & Fiskum, G. M. (2011) · Journal of Neuroscience Research · doi:10.1002/jnr.22709 · Cited by 25

Endoplasmic reticulum stress contributes to heart protection induced by cyclophilin D inhibition

Belaïdi, E., Décorps, J., Augeul, L., Durand, A., & Ovize, M. (2013) · Basic Research in Cardiology · doi:10.1007/s00395-013-0363-z · Cited by 23

Exogenous supplemental NAD+ protect myocardium against myocardial ischemic/reperfusion injury in swine model.

Zhai, X., Han, W., Wang, M., Guan, S., & Qu, X. (2019) · PubMed Central · Cited by 23

Modulation of Mitochondrial Transition Pore Components by Thyroid Hormone

Yehuda‐Shnaidman, E., Kalderon, B., & Bar‐Tana, J. (2005) · Endocrinology · doi:10.1210/en.2004-1161 · Cited by 23

Milrinone-Induced Pharmacological Preconditioning in Cardioprotection: Hints for a Role of Mitochondrial Mechanisms

Raupach, A., Reinle, J., Stroethoff, M., Mathes, A., Heinen, A., Hollmann, M. W., Huhn, R., & Bunte, S. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8040507 · Cited by 22

Nigella sativa attenuates myocardial ischemic reperfusion injury in rats

Seif, A. A. (2013) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-013-0272-5 · Cited by 22

A Panoramic Overview of Mitochondria and Mitochondrial Redox Biology

Kim, A. (2014) · Toxicological Research · doi:10.5487/tr.2014.30.4.221 · Cited by 22

Detecting mitochondrial permeability transition by confocal imaging of intact cells pinocytically loaded with calcein

Jones, R. A., Smail, A., & Wilson, M. R. (2002) · European Journal of Biochemistry · doi:10.1046/j.1432-1033.2002.03087.x · Cited by 22

A fluorescence-based technique for screening compounds that protect against damage to brain mitochondria

Kristián, T., & Fiskum, G. M. (2004) · Brain Research Protocols · doi:10.1016/j.brainresprot.2004.05.001 · Cited by 22

The Mitochondria‐Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age

Mitchell, W., Pharaoh, G. A., Tyshkovskiy, A., Campbell, M., Marcinek, D. J., & Gladyshev, V. N. (2025) · Aging Cell · doi:10.1111/acel.70026 · Cited by 23

Nitrite Confers Preconditioning and Cytoprotection After Ischemia/Reperfusion Injury Through the Modulation of Mitochondrial Function

Portella, R. D. L., Bickta, J., & Shiva, S. (2015) · Antioxidants and Redox Signaling · doi:10.1089/ars.2015.6260 · Cited by 21

Rho GTPase regulation of reactive oxygen species generation and signalling in platelet function and disease

Ngo, A. T. P., Parra‐Izquierdo, I., Aslan, J. E., & McCarty, O. J. T. (2021) · Small GTPases · doi:10.1080/21541248.2021.1878001 · Cited by 21

Frequent biomarker analysis in the isolated perfused heart reveals two distinct phases of reperfusion injury

Povlsen, J. A., Løfgren, B., Dalgas, C., Jespersen, N. R., Johnsen, J., & Bøtker, H. E. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.11.035 · Cited by 21

Desflurane-induced post-conditioning against myocardial infarction is mediated by calcium-activated potassium channels: role of the mitochondrial permeability transition pore

Stumpner, J., Lange, M., Beck, A., Smul, T. M., Lotz, C., Kehl, F., Roewer, N., & Redel, A. (2012) · British Journal of Anaesthesia · doi:10.1093/bja/aer496 · Cited by 21

A Regulatory Role of NAD Redox Status on Flavin Cofactor Homeostasis inS. cerevisiaeMitochondria

Giancaspero, T. A., Locato, V., & Barile, M. (2013) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2013/612784 · Cited by 22

Targeting Endoplasmic Reticulum and/or Mitochondrial Ca2+ Fluxes as Therapeutic Strategy for HCV Infection

Scrima, R., Piccoli, C., Moradpour, D., & Capitanio, N. (2018) · Frontiers in Chemistry · doi:10.3389/fchem.2018.00073 · Cited by 21

Imaging of reactive oxygen species burst from mitochondria using laser scanning confocal microscopy

Xu, J., Hao, Z., Gou, X., Tian, W., Jin, Y., Cui, S., Guo, J., Sun, Y., Wang, Y., & Xu, Z. (2013) · Microscopy Research and Technique · doi:10.1002/jemt.22207 · Cited by 20

Attenuation of gentamicin‐induced nephrotoxicity: trimetazidine versus N‐acetyl cysteine

Rodríguez, L. C. D. L. C., Araujo, C. R., Posleman, S. E., & Rey, M. R. (2010) · Journal of Applied Toxicology · doi:10.1002/jat.1502 · Cited by 20

Opioid δ1 and δ2 Receptor Agonist Attenuate Myocardial Injury Via mPTP in Rats With Acute Hemorrhagic Shock

Zeng, X., Zhao, X., Yang, Y., Kuai, J., Gao, C., Yu, D., Zhao, H., Chai, W., & Yao, L. (2010) · Journal of Surgical Research · doi:10.1016/j.jss.2009.12.017 · Cited by 20

Cardiac Sodium Channel Mutations

Liu, M., Yang, K., & Dudley, S. C. (2016) · Current topics in membranes · doi:10.1016/bs.ctm.2015.12.004 · Cited by 20

The mitochondrial ADPR link between Ca 2+ store release and Ca 2+ influx channel opening in immune cells

Ayub, K., & Hallett, M. B. (2004) · The FASEB Journal · doi:10.1096/fj.04-1888hyp · Cited by 20

Postconditioning: from experimental proof to clinical concept

Mewton, N., Ivanés, F., Cour, M., & Ovize, M. (2010) · Disease Models & Mechanisms · doi:10.1242/dmm.004309 · Cited by 19

Hepatitis C virus, mitochondria and auto/mitophagy: Exploiting a host defense mechanism

Ruggieri, V. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i10.2624 · Cited by 20

Comparison of multiple doses of cyclosporine A on germ cell apoptosis and epididymal sperm parameters after testicular ischemia/reperfusion in rats

Yazdani, I., Majdani, R., Ghasemnejad‐Berenji, M., & Dehpour, A. R. (2019) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2019.104271 · Cited by 19

Mitochondrial proteomics as a selective tool for unraveling Parkinson’s disease pathogenesis

Pienaar, I. S., Dexter, D. T., & Burkhard, P. R. (2010) · Expert Review of Proteomics · doi:10.1586/epr.10.8 · Cited by 19

Induction of the mitochondrial permeability transition by the DNA alkylating agent N-methyl-N′-nitro-N-nitrosoguanidine. Sorting cause and consequence of mitochondrial dysfunction

Dodoni, G., Canton, M., Petronilli, V., Bernardi, P., & Lisa, F. D. (2004) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2004.05.005 · Cited by 19

Yiqihuoxue decoction protects against post-myocardial infarction injury via activation of cardiomyocytes PGC-1α expression

Li, F., Guo, S., Wang, C., Huang, X., Wang, H., Tan, X., Cai, Q., Wu, J., Zhang, Y., Chen, X., et al. (2018) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-018-2319-1 · Cited by 19

Microglia activation induces oxidative injury and decreases SIRT3 expression in dopaminergic neuronal cells

Jiang, D., Ma, Y., Wang, Y., Lu, H., Mao, S., & Zhao, S.-H. (2019) · Journal of Neural Transmission · doi:10.1007/s00702-019-02005-z · Cited by 18

Kinetics of Myoglobin Redox Form Stabilization by Malate Dehydrogenase

Mohan, A., Muthukrishnan, S., Hunt, M. C., Barstow, T. J., & Houser, T. A. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf100639n · Cited by 18

Emerging interactions between mitochondria and NAD+ metabolism in cardiometabolic diseases

Nasuhidehnavi, A., Zarzycka, W., Gorecki, I., Chiao, Y. A., & Lee, C. F. (2024) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2024.07.010 · Cited by 20

Cardiac Mitochondrial Alterations Observed in Hyperglycaemic Rats - What Can We Learn From Cell Biology?

Oliveira, P. J. (2005) · Current Diabetes Reviews · doi:10.2174/1573399052952578 · Cited by 17

Developmental determinants of cardiac sensitivity to hypoxia

Ostadal, B., Ostadalova, I., Kolář, F., & Sedmera, D. (2014) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2013-0498 · Cited by 17

Developmental Changes of the Sensitivity of Cardiac and Liver Mitochondrial Permeability Transition Pore to Calcium Load and Oxidative Stress

Drahota, Z., Milerová, M., Endlicher, R., Rychtrmoc, D., Červinková, Z., & Ošťádal, B. (2012) · Physiological Research · doi:10.33549/physiolres.932377 · Cited by 17

A Synthetic Epoxydocosapentaenoic Acid Analogue Ameliorates Cardiac Ischemia/Reperfusion Injury: The Involvement of the Sirtuin 3–NLRP3 Pathway

Darwesh, A. M., Bassiouni, W., Adebesin, A. M., Mohammad, A. S., Falck, J. R., & Seubert, J. M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155261 · Cited by 17

Cardioprotecive Properties of Known Agents in Rat Ischemia-Reperfusion Model Under Clinically Relevant Conditions: Only the NAD Precursor Nicotinamide Riboside Reduces Infarct Size in Presence of Fentanyl, Midazolam and Cangrelor, but Not Propofol

Xiao, Y., Phelp, P. G., Wang, Q., Bakker, D., Nederlof, R., Hollmann, M. W., & Zuurbier, C. J. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.712478 · Cited by 16

Improved Mitochondrial Bioenergetics by Anesthetic Preconditioning During and After 2 Hours of 27°C Ischemia in Isolated Hearts

An, J., Camara, A. K. S., Riess, M. L., Rhodes, S. S., Varadarajan, S. G., & Stowe, D. F. (2005) · Journal of Cardiovascular Pharmacology · doi:10.1097/01.fjc.0000175238.18702.40 · Cited by 16

Hypothyroidism provides resistance to kidney mitochondria against the injury induced by renal ischemia-reperfusion

Zazueta, C., Franco, M., Correa, F., Garcı́a, N., Santamaría, J., Abundis, E. M., & Chávez, E. (2007) · Life Sciences · doi:10.1016/j.lfs.2006.12.023 · Cited by 16

Role of poly(ADP-ribose) polymerase activity in imatinib mesylate-induced cell death

Moehring, A., Wohlbold, L., Aulitzky, W. E., & van der Kuip, H. (2005) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401608 · Cited by 16

The Role of Ranolazine in Heart Failure-Current Concepts

Kourampi, I., Katsioupa, M., Oikonomou, E. K., Tsigkou, V., Marinos, G., Goliopoulou, A., Κατσαρού, Ο., Kalogeras, K. I., Theofilis, P., Tsatsaragkou, A., et al. (2023) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2023.09.066 · Cited by 15

Mitochondrial quality control: Biochemical mechanism of cardiovascular disease

Inferrera, F., Marino, Y., Genovese, T., Cuzzocrea, S., Fusco, R., & Paola, R. D. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2025.119906 · Cited by 16

Gender-dependent Metabolic Remodeling During Heart Preservation in Cardioplegic Celsior and Histidine Buffer Solution

Alves, M., Oliveira, P. F., Martins, F. O., Oliveira, P. J., & Carvalho, R. (2012) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e3182391d17 · Cited by 12

Cardioprotection for percutaneous coronary intervention — Reperfusion quality as well as quantity

Giblett, J. P., West, N. E. J., & Hoole, S. P. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.10.041 · Cited by 15

Estrogen deprivation aggravates cardiometabolic dysfunction in obese-insulin resistant rats through the impairment of cardiac mitochondrial dynamics

Minta, W., Palee, S., Mantor, D., Sutham, W., Jaiwongkam, T., Kerdphoo, S., Pratchayasakul, W., Kumfu, S., Chattipakorn, S. C., & Chattipakorn, N. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2018.01.006 · Cited by 16

Toxic effect of high glucose on cardiomyocytes, H9c2 cells: Induction of oxidative stress and ameliorative effect of trolox

Davargaon, R. S., Devi, S. A., & Subramanyam Muthangi, V., V (2018) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.22272 · Cited by 15

Preconditioning or Postconditioning with 8-Br-cAMP-AM Protects the Heart against Regional Ischemia and Reperfusion: A Role for Mitochondrial Permeability Transition

Халиулин, И. Г., Ascione, R., Маслов, Л. Н., Amal, H., & Suleiman, M. S. (2021) · Cells · doi:10.3390/cells10051223 · Cited by 15

Direct, pleiotropic protective effect of cyclosporin A against simulated ischemia-induced injury in isolated cardiomyocytes

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