Constitutive Activation of NF-κB and Secretion of Interleukin-8 Induced by the G Protein-coupled Receptor of Kaposi's Sarcoma-associated Herpesvirus Involve Gα13 and RhoA
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One pathological feature of prion disease is activation of microglia and accumulation of astrocytes, detectable prior to clinical symptoms and other signs of neurodegeneration.
“As is the case in other neurodegenerative conditions, such as Alzheimer's disease, one of the pathological features of disease is the activation of the brain's resident immune cells, the microglia, and the accumulation of astrocytes. In many instances, this feature can be detected prior to clinical symptoms and other signs of neurodegeneration, such as spongiosis and neuronal cell death become app”
From MicroRNA 146a (miR-146a) Is Over-Expressed during Prion Disease and Modulates the Innate Immune Response and the Microglial Activation State (2012) · cites this paper as [3]
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Cites
Interleukin-8 as a macrophage-derived mediator of angiogenesis
Koch, A. E., Polverini, P. J., Kunkel, S. L., Harlow, L. A., DiPietro, L. A., Elner, V. M., Elner, S. G., & Strieter, R. M. (1992) · Science · doi:10.1126/science.1281554 · Cited by 2,135 · see citing works
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Research works printed but not linked: 6
- Lukiw, W. J., Pelaez, R. P., Martinez, J., and Bazan, N. G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3914 -3919
- Fuhlbrigge, R. C., Fine, S. M., Unanue, E. R., and Chaplin, D. D. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 5649 -5653
- Weng, Z., Fluckiger, A. C., Nisitani, S., Wahl, M. I., Le, L. Q., Hunter, C. A., Fernal, A. A., Le Beau, M. M., and Witte, O. N. (1998) Proc. Natl. Acad. Sci.
- Kabarowski, J. H., Feramisco, J. D., Le, L. Q., Gu, J. L., Luoh, S. W., Simon, M. I., and Witte, O. N. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 12109 -12114
- Belperio, J. A., Keane, M. P., Arenberg, D. A., Addison, C. L., Ehlert, J. E., Burdick, M. D., and Strieter, R. M. (2000) J. Leukocyte Biol. 68, 1-8
- Addison, C. L., Daniel, T. O., Burdick, M. D., Liu, H., Ehlert, J. E., Xue, Y. Y., Buechi, L., Walz, A., Richmond, A., and Strieter, R. M. (2000) J. Immunol. 165, 5269 -5277
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Saba, R., Gushue, S., Huzarewich, R. L. C. H., Manguiat, K., Medina, S., Robertson, C., & Booth, S. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030832 · Cited by 151 · see citing works
- Authors
- Shepard, L. W., Yang, M., Xie, P., Browning, D. D., Voyno-Yasenetskaya, T., Kozasa, T., & Ye, R. D.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2001-12
- Volume
- 276
- Issue
- 49
- Pages
- 45979-45987
- ISSN
- 0021-9258
- Cited by
- 95
- References
- 1
- Language
- en
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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