Covalent Peroxisome Proliferator-activated Receptor γ Adduction by Nitro-fatty Acids

Schopfer, Francisco J., Cole, Marsha P., Groeger, Alison L., Chen, Chen-Shan, Khoo, Nicholas K.H., Woodcock, Steven R., Golin-Bisello, Franca, Motanya, U.Nkiru +12 more·2010·Journal of Biological Chemistry
DOI 10.1074/jbc.m109.091512

Cited by (176)

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  28. Induction of peroxisome proliferator activated receptor γ (PPARγ) mediated gene expression and inhibition of induced nitric oxide production by Maerua subcordata (Gilg) DeWolf
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  29. Importance of 5/6-aryl substitution on the pharmacological profile of 4ʹ-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1ʹ-biphenyl]-2-carboxylic acid derived PPARγ agonists
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  30. Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies
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  40. Nitro‐fatty acids‐mediated nitroalkylation modulates fine‐tuning catalase antioxidant function during salinity stress in plants
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  42. Synthesis of 5-trifluoromethyl-2-sulfonylpyridine PPARβ/δ antagonists: Effects on the affinity and selectivity towards PPARβ/δ
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  44. Effects of fatty acid nitroalkanes on signal transduction pathways and airway macrophage activation
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  46. Nitro-Fatty Acids: Synthesis, Properties, and Role in Biological System
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  47. Nitro-oleic acid is a novel anti-oxidative therapy for diabetic kidney disease
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  48. Adipocyte-specific Nrf2 deletion negates nitro-oleic acid benefits on glucose tolerance in diet-induced obesity
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  51. Coplanar PCB-induced inflammation and dietary interventions
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  66. Additional file 1 of Induction of peroxisome proliferator activated receptor γ (PPARγ) mediated gene expression and inhibition of induced nitric oxide production by Maerua subcordata (Gilg) DeWolf
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  72. BindingDB Entry 50039777: Total synthesis and dual PPARa/¿ agonist effects of amorphastilbol and its synthetic derivatives.
    BindingDB · 2013 · UC San Diego
  73. BindingDB Entry 50048975: Importance of 5/6-aryl substitution on the pharmacological profile of 4'-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid derived PPAR¿ agonists.
    BindingDB · 2019 · UC San Diego
  74. BindingDB Entry 50046852: Synthesis of 5-trifluoromethyl-2-sulfonylpyridine PPARß/d antagonists: Effects on the affinity and selectivity towards PPARß/d.
    BindingDB · 2017 · UC San Diego
  75. BindingDB Entry 50048178: Evaluation of selected 3D virtual screening tools for the prospective identification of peroxisome proliferator-activated receptor (PPAR)¿ partial agonists.
    BindingDB · 2018 · UC San Diego
  76. BindingDB Entry 50045740: Synthesis, biological evaluation and molecular modeling studies of the PPARß/d antagonist CC618.
    BindingDB · 2016 · UC San Diego