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Cited by 73

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

LRP6 Protein Regulates Low Density Lipoprotein (LDL) Receptor-mediated LDL Uptake

Ye, Zhi-jia, Go, Gwang-Woong, Singh, Rajvir, Liu, Wenzhong, Keramati, Ali Reza, Mani, Arya·2012·Journal of Biological Chemistry
DOI 10.1074/jbc.m111.295287
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Crossref · 10.1074/jbc.m111.295287

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  • There are LDLR-independent mechanisms of LDL clearance from plasma, but these pathways have not been fully elucidated.

    “There are LDLR-independent mechanisms of LDL clearance from plasma, but these pathways have not been fully elucidated (16).”

    From Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism (2012) · cites this paper as [16]

    The Results section shows LDLR-independent LDL uptake in LDLR-deficient CHO cells, and the Discussion says further investigation of LRP6 trafficking is needed. The paper does not establish LDLR-independent clearance from plasma; its evidence is for cellular uptake, so the plasma-level claim goes beyond it. Page numbers are unavailable in our copy. (LLM, conf=0.86)

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Citations

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Research works printed but not linked: 26

  1. Rahilly-Tierney, 2009, Low density lipoprotein reduction and magnitude of cardiovascular risk reduction, Prev. Cardiol., 12, 80, 10.1111/j.1751-7141.2008.00018.x · DOI
  2. Varma, 2005, Prevalence of adequate control of increased serum low density lipoprotein cholesterol in self-pay or Medicare patients versus Medicaid or private insurance patients followed in a University General Medicine Clinic, Am. J. Cardiol., 95, 269, 10.1016/j.amjcard.2004.08.095 · DOI
  3. Hobbs, 1989, Evidence for a dominant gene that suppresses hypercholesterolemia in a family with defective low density lipoprotein receptors, J. Clin. Invest., 84, 656, 10.1172/JCI114212 · DOI
  4. Hobbs, 1990, The LDL receptor locus in familial hypercholesterolemia. Mutational analysis of a membrane protein, Annu. Rev. Genet, 24, 133, 10.1146/annurev.ge.24.120190.001025 · DOI · Paper page
  5. Hobbs, 1992, Molecular genetics of the LDL receptor gene in familial hypercholesterolemia, Hum. Mutat., 1, 445, 10.1002/humu.1380010602 · DOI · Paper page
  6. Russell, 1986, The LDL receptor in familial hypercholesterolemia. Use of human mutations to dissect a membrane protein, Cold Spring Harbor Symp. Quant. Biol., 51, 811, 10.1101/SQB.1986.051.01.094 · DOI
  7. Liu, 2008, Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance, Circ. Res., 103, 1280, 10.1161/CIRCRESAHA.108.183863 · DOI
  8. Mani, 2007, LRP6 mutation in a family with early coronary disease and metabolic risk factors, Science, 315, 1278, 10.1126/science.1136370 · DOI
  9. Tomaszewski, 2009, A common variant in low density lipoprotein receptor-related protein 6 gene (LRP6) is associated with LDL-cholesterol, Arterioscler. Thromb. Vasc. Biol., 29, 1316, 10.1161/ATVBAHA.109.185355 · DOI
  10. Tiscornia, 2006, Design and cloning of lentiviral vectors expressing small interfering RNAs, Nat. Protoc., 1, 234, 10.1038/nprot.2006.36 · DOI
  11. Basu, 1981, Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts, Cell, 24, 493, 10.1016/0092-8674(81)90340-8 · DOI · Paper page
  12. Loeffler, 2007, Lipoprotein lipase-facilitated uptake of LDL is mediated by the LDL receptor, J. Lipid Res., 48, 288, 10.1194/jlr.M600292-JLR200 · DOI
  13. Yamamoto, 2006, Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of β-catenin, Dev. Cell, 11, 213, 10.1016/j.devcel.2006.07.003 · DOI
  14. Boucrot, 2010, Roles of AP-2 in clathrin-mediated endocytosis, PLoS One, 5, e10597, 10.1371/journal.pone.0010597 · DOI
  15. Yokomori, 2009, Caveolin-1 and Rac regulate endothelial capillary-like tubular formation and fenestral contraction in sinusoidal endothelial cells, Liver Int., 29, 266, 10.1111/j.1478-3231.2008.01891.x · DOI
  16. Carozzi, 2000, Role of cholesterol in developing T-tubules. Analogous mechanisms for T-tubule and caveolae biogenesis, Traffic, 1, 326, 10.1034/j.1600-0854.2000.010406.x · DOI
  17. Fernández-Hernando, 2009, Genetic evidence supporting a critical role of endothelial caveolin-1 during the progression of atherosclerosis, Cell Metab., 10, 48, 10.1016/j.cmet.2009.06.003 · DOI
  18. Fernández-Hernando, 2010, Endothelial-specific overexpression of caveolin-1 accelerates atherosclerosis in apolipoprotein E-deficient mice, Am. J. Pathol., 177, 998, 10.2353/ajpath.2010.091287 · DOI
  19. Goldstein, 1973, Familial hypercholesterolemia. Identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol, Proc. Natl. Acad. Sci. U.S.A., 70, 2804, 10.1073/pnas.70.10.2804 · DOI · Paper page
  20. Kokubu, 2004, Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis, Development, 131, 5469, 10.1242/dev.01405 · DOI
  21. Lindvall, 2009, The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development, PLoS One, 4, e5813, 10.1371/journal.pone.0005813 · DOI
  22. Nesterov, 1995, Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism, J. Biol. Chem., 270, 6320, 10.1074/jbc.270.11.6320 · DOI
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Metadata

Authors
Ye, Z.-J., Go, G.-W., Singh, R., Liu, W., Keramati, A. R., & Mani, A.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
2012-01
Volume
287
Issue
2
Pages
1335-1344
ISSN
0021-9258
DOI
10.1074/jbc.m111.295287
Cited by
73
References
2
Language
en
Licence

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