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Novel AKT1-GLI3-VMP1 Pathway Mediates KRAS Oncogene-induced Autophagy in Cancer Cells
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“TFE3 and MITF, two other members of the MiT/TFE family of transcription factors, in some cases can compensate for TFEB and are regulated in a similar manner [967, 971, 972].”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [967]
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“TFEB activity is regulated by starvation and is controlled by both MAPK1/ERK2-, MTOR-, and AKT-mediated phosphorylation at specific serine residues [943, 964-967]; thus, it can serve as a new tool for monitoring transcriptional regulation connected with autophagy.”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [967]
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Cites
Induction of autophagy and inhibition of tumorigenesis by beclin 1
Liang, X. H., Jackson, S., Seaman, M., Brown, K., Kempkes, B., Hibshoosh, H., & Levine, B. (1999) · Nature · doi:10.1038/45257 · Cited by 3,347
Pancreatic cancers require autophagy for tumor growth
Yang, S., Wang, X., Contino, G., Liesa, M., Sahin, E., Ying, H., Bause, A., Li, Y., Stommel, J. M., Dell'Antonio, G., et al. (2011) · Genes & Development · doi:10.1101/gad.2016111 · Cited by 1,498
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
Guo, J. Y., Chen, H.-Y., Mathew, R., Fan, J., Strohecker, A. M., Karsli-Uzunbas, G., Kamphorst, J. J., Chen, G., Lemons, J. M. S., Karantza, V., et al. (2011) · Genes & Development · doi:10.1101/gad.2016311 · Cited by 1,323
The Pancreatitis-induced Vacuole Membrane Protein 1 Triggers Autophagy in Mammalian Cells
Ropolo, A., Grasso, D., Pardo, R., Sacchetti, M. L., Archange, C., Re, A. L., Seux, M., Nowak, J., Gonzalez, C. D., Iovanna, J. L., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m706956200 · Cited by 223
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Flagged first, then by citations
Research works printed but not linked: 29
- Levine, 2008, Autophagy in the pathogenesis of disease, Cell., 132, 27, 10.1016/j.cell.2007.12.018 · DOI · Paper page
- Lum, 2005, Autophagy in metazoans: Cell survival in the land of plenty, Nat. Rev. Mol. Cell Biol., 6, 439, 10.1038/nrm1660 · DOI
- Kundu, 2008, Autophagy: Basic principles and relevance to disease, Annu. Rev. Pathol., 3, 427, 10.1146/annurev.pathmechdis.2.010506.091842 · DOI · Paper page
- Chen, 2010, Autophagy and tumorigenesis, FEBS Lett., 584, 1427, 10.1016/j.febslet.2009.12.034 · DOI
- Kim, 2011, Involvement of mitophagy in oncogenic K-Ras-induced transformation: Overcoming a cellular energy deficit from glucose deficiency, Autophagy., 7, 1187, 10.4161/auto.7.10.16643 · DOI
- White, 2010, Role of autophagy in suppression of inflammation and cancer, Curr. Opin. Cell Biol., 22, 212, 10.1016/j.ceb.2009.12.008 · DOI
- Amaravadi, 2007, Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma, J. Clin. Invest., 117, 326, 10.1172/JCI28833 · DOI
- Rosenfeldt, 2011, The multiple roles of autophagy in cancer, Carcinogenesis., 32, 955, 10.1093/carcin/bgr031 · DOI
- Notte, 2011, Autophagy as a mediator of chemotherapy-induced cell death in cancer, Biochem. Pharmacol., 82, 427, 10.1016/j.bcp.2011.06.015 · DOI
- Vaccaro, 2008, A novel mammalian trans-membrane protein reveals an alternative initiation pathway for autophagy, Autophagy., 4, 388, 10.4161/auto.5656 · DOI
- Grasso, 2011, Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death, J. Biol. Chem., 286, 8308, 10.1074/jbc.M110.197301 · DOI
- Grasso, 2009, Autophagy and VMP1 expression are early cellular events in experimental diabetes, Pancreatology., 9, 81, 10.1159/000178878 · DOI
- Grasso, 2012, Autophagy in pancreatic cancer, Int. J. Cell Biol., 2012, 760498, 10.1155/2012/760498 · DOI
- Elsawa, 2011, GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment, J. Biol. Chem., 286, 21524, 10.1074/jbc.M111.234146 · DOI
- Kim, 2011, Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation, J. Biol. Chem., 286, 12924, 10.1074/jbc.M110.138958 · DOI
- Pardo, 2010, Gemcitabine induces the VMP1-mediated autophagy pathway to promote apoptotic death in human pancreatic cancer cells, Pancreatology., 10, 19, 10.1159/000264680 · DOI
- Tuveson, 2005, Ductal pancreatic cancer in humans and mice, Cold Spring Harb. Symp. Quant. Biol., 70, 65, 10.1101/sqb.2005.70.040 · DOI
- Pérez-Mancera, 2006, Physiological analysis of oncogenic K-ras, Methods Enzymol., 407, 676, 10.1016/S0076-6879(05)07053-9 · DOI
- Mariño, 2011, Autophagy in Ras-induced malignant transformation: Fatal or vital?, Mol. Cell., 42, 1, 10.1016/j.molcel.2011.03.003 · DOI
- Lock, 2011, Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation, Mol. Biol. Cell., 22, 165, 10.1091/mbc.e10-06-0500 · DOI · Paper page
- Lock, 2011, Ras, autophagy and glycolysis, Cell Cycle., 10, 1516, 10.4161/cc.10.10.15434 · DOI
- Hingorani, 2003, Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse, Cancer Cell., 4, 437, 10.1016/S1535-6108(03)00309-X · DOI · Paper page
- Hui, 2011, Gli proteins in development and disease, Annu. Rev. Cell Dev. Biol., 27, 513, 10.1146/annurev-cellbio-092910-154048 · DOI
- Stecca, 2010, Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals, J. Mol. Cell. Biol., 2, 84, 10.1093/jmcb/mjp052 · DOI
- Nolan-Stevaux, 2009, GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation, Genes Dev., 23, 24, 10.1101/gad.1753809 · DOI
- Akimaru, 1997, Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signaling, Nature., 386, 735, 10.1038/386735a0 · DOI
- Lin, 2008, Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos, Dev. Dyn., 237, 928, 10.1002/dvdy.21479 · DOI
- Yauch, 2008, A paracrine requirement for hedgehog signaling in cancer, Nature., 455, 406, 10.1038/nature07275 · DOI
- Tian, 2010, C. elegans screen identifies autophagy genes specific to multicellular organisms, Cell., 141, 1042, 10.1016/j.cell.2010.04.034 · DOI · Paper page
Cited by
Sorted by citations
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy · doi:10.1080/15548627.2015.1100356 · Cited by 5,894
Self-citationGuidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy · doi:10.1080/15548627.2020.1797280 · Cited by 2,897
Self-citationThe metabolic landscape of RAS-driven cancers from biology to therapy
Mukhopadhyay, S., Vander Heiden, M. G., & McCormick, F. (2021) · Nature Cancer · doi:10.1038/s43018-021-00184-x · Cited by 315
Kaur, G., Muthumalage, T., & Rahman, I. (2023) · Aging Cell · doi:10.1111/acel.13850 · Cited by 53
Metadata
- Authors
- Lo Ré, A. E., Fernández-Barrena, M. G., Almada, L. L., Mills, L. D., Elsawa, S. F., Lund, G., Ropolo, A., Molejon, M. I., Vaccaro, M. I., & Fernandez-Zapico, M. E.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2012-07
- Volume
- 287
- Issue
- 30
- Pages
- 25325-25334
- ISSN
- 0021-9258
- Cited by
- 87
- References
- 4
- Language
- en
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