Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21

Dunshee, Diana Ronai, Bainbridge, Travis W., Kljavin, Noelyn M., Zavala-Solorio, Jose, Schroeder, Amy C., Chan, Ruby, Corpuz, Racquel, Wong, Manda, Zhou, Wei, Deshmukh, Gauri, Ly, Justin, Sutherlin, Daniel P., Ernst, James A., Sonoda, Junichiro·2016·Journal of Biological Chemistry
DOI 10.1074/jbc.m115.710582

Cited by (156)

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  15. Sitagliptin reduces FAP-activity and increases intact FGF21 levels in patients with newly detected glucose abnormalities
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  16. Fibroblast activation protein enzyme deficiency prevents liver steatosis, insulin resistance and glucose intolerance and increases fibroblast growth factor-21 in diet induced obese mice
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  30. Serum fibroblast growth factor 21 is a novel biomarker of cachexia in chronic liver disease
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  34. Mistranslation drives alterations in protein levels and the effects of a synonymous variant at the FGF21 locus
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  36. FAP
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  45. Additional file 2 of The cross talk between type II diabetic microenvironment and the regenerative capacities of human adipose tissue-derived pericytes: a promising cell therapy
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  50. Valsartan alleviates acetaminophen-induced hepatotoxicity by activating fibroblast growth factor 21 in acute liver injury in mice
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  54. Molecular advancements in targeting fibroblast activation protein (FAP) in cancer therapies
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  55. BindingDB Entry 50012408: Identification of BR102910 as a selective fibroblast activation protein (FAP) inhibitor.
    BindingDB · 2022 · UC San Diego
  56. BindingDB Entry 50003252: Fibrogenic Disorders in Human Diseases: From Inflammation to Organ Dysfunction.
    BindingDB · 2020 · UC San Diego