Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis

Zhang, Xuejun, Kurnasov, Oleg V., Karthikeyan, Subramanian, Grishin, Nick V., Osterman, Andrei L., Zhang, Hong·2003·Journal of Biological Chemistry

Cited by (137)

Items 101–137 of 137

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  2. Identification of a nicotinamide/nicotinate mononucleotide adenylyltransferase in Giardia lamblia (GlNMNAT)
    Nicolás Forero-Baena, Diana Milena Sánchez-Lancheros, July Constanza Buitrago, Victor Bustos, María Helena Ramírez-Hernández · 2015 · Biochimie Open
  3. Methods for Using a Genetically Encoded Fluorescent Biosensor to Monitor Nuclear NAD+
    Michael S. Cohen, Melissa L. Stewart, Richard H. Goodman, Xiaolu A. Cambronne · 2018 · Methods in molecular biology
  4. SYNTHESIS AND BIOLOGICAL EVALUATION OF NAD ANALOGS AS HUMAN PYRIDINE NUCLEOTIDE ADENYLYLTRANSFERASE INHIBITORS
    Palmarisa Franchetti, Riccardo Petrelli, Loredana Cappellacci, Michela Pasqualini, Patrizia Vita, Leonardo Sorci, Francesca Mazzola, Nadia Raffaelli, Giulio Magni · 2005 · Nucleosides Nucleotides & Nucleic Acids
  5. Loss of hepatic Nmnat1 has no impact on diet-induced fatty liver disease
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  6. The mouse nicotinamide mononucleotide adenylyltransferase chaperones diverse pathological amyloid client proteins
    Chengan Huang, Jinxia Lu, Xiaojuan Ma, Jiali Qiang, Chuchu Wang, Cong Liu, Yanshan Fang, Yaoyang Zhang, Lin Jiang, Dan Li et al. · 2022 · Journal of Biological Chemistry
  7. Assessing the inhibitory effects of some secondary amines, thioureas and 1,3-dimethyluracil conjugates of (-)-cytisine and thermopsine on the RNA-dependent RNA polymerase of SARS-CoV-1 and SARS-CoV-2
    Yeh Chen, Mann‐Jen Hour, Chen‐Sheng Lin, Young-Sheng Chang, Zan-Yu Chen, Alena V. Koval’skaya, Wen‐Chi Su, Inna Petrovna Tsypysheva, Cheng‐Wen Lin · 2024 · Bioorganic & Medicinal Chemistry Letters
  8. Method Development for Determining β-Nicotinamide Mononucleotide (NMN) in Cosmetics Using m-PFC–HPLC
    Tao Lan, Wenyu Zhang, Hongtao Chu, Zhenyu Yun, Bin Qu · 2025 · Journal of AOAC International
  9. NMNAT3 deficiency: a novel red blood cell enzymopathy causing hemolysis by altering NAD levels and glycolysis
    Titine J.J. Ruiter, Brigitte A. van Oirschot, Esmé Waanders, Klaas Koop, Wouter W. van Solinge, Richard van Wijk, Judith J M Jans, Marije Bartels · 2025 · Blood
  10. Obtaining high yield recombinant Enterococcus faecium nicotinate nucleotide adenylyltransferase for X-ray crystallography and biophysical studies
    Olamide Jeje, Ramesh Pandian, Yasien Sayed, Ikechukwu Achilonu · 2023 · International Journal of Biological Macromolecules
  11. The adenine nucleotide translocase—a carrier protein potentially required for mitochondrial generation of NAD
    Mathias Ziegler · 2005 · Biochemistry (Moscow)
  12. Nicotinamide adenine dinucleotide+ metabolism biomarkers in malignant gliomas
    Antonio Lucena-Cacace, Manuel P. Jiménez-García, EvaM Verdugo-Sivianes · 2016 · Cancer translational medicine
  13. Abundant organic nitrogen enhances natamycin biosynthesis by increasing NAD(P) metabolic pathway activity in Streptomyces gilvosporeus F607
    Zhihui Meng, Minghui Yu, Jiahui Wang, Haijun Li, Wenhui Gao, Peitong Yang, Xingyu Cui, Peipei Zhang, Jiafang Fu, Guangxiang Cao et al. · 2025 · Frontiers in Microbiology
  14. NAD: Metabolism and Regulatory Functions
    Mathias Ziegler · 2008 · Springer eBooks
  15. Cloning, Expression and Characterization of Mouse (Mus musculus) Nicotinamide 5-Mononucleotide Adenylyltransferase-2
    David W. Raches, Suhong Xiao, Praveen Kusumanchi, Joel Aaron Yalowitz, Paresh C. Sanghani, Eric C. Long, Asok C. Antony, Hiremagalur N. Jayaram · 2011 · Medicinal Chemistry
  16. Metabolic Regulation of Lysine Acetylation: Implications in Cancer
    Siddharth Singh, Parijat Senapati, Tapas Kumar Kundu · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
  17. Structural insights into Plasmodium falciparum nicotinamide mononucleotide adenylyltransferase: oligomeric assembly
    Luis Ernesto Contreras-Rodríguez, Catherin Yizet Marin-Mogollon, Lina Marcela Sánchez-Mejía, María Helena Ramírez-Hernández · 2018 · Memórias do Instituto Oswaldo Cruz
  18. SEARCHING FOR NEW ANTIMICROBIAL AGENTS BY TARGETING BACTERIAL NAD METABOLISM: EVALUATION OF FRENTIZOLE DERIVATIVES SELECTED BY MOLECULAR DOCKING
    Michaela Hympánová, Tomas Kucera, Ondřej Benek, Jan Korábečný, Jan Marek · 2020 · Military Medical Science Letters
  19. Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase
    Tasvi Daya, Olamide Jeje, Reabetswe Maake, Chinyere Aloke, Thandeka Khoza, Ikechukwu Achilonu · 2022 · The Protein Journal
  20. Functional Characterisation of Three Human Nicotinamide Mononucleotide Adenylyltransferases
    Corinna Lau · 2008 · NORA - Norwegian Open Research Archives
  21. Etude de la biosynthese du nad chez les plantes : conséquences physiologiques de sa manipulation chez Arabidopsis thaliana
    Pierre Pétriacq · 2011
  22. Tracking neuronal content using capillary electrophoresis with multiphoton excitation of fluorescence
    Dana D. Wise · 2005 · Texas ScholarWorks (Texas Digital Library)
  23. Strategies to Potentiate the Cellular Poly(ADP-ribosyl)ation Response to DNA Damage
    Andrea Kunzmann · 2009
  24. NicotinamideMononucleotideAdenylyltransferase ExpressioninMitochondrialMatrixDelaysWallerian Degeneration
    Toshiyuki Araki · 2009
  25. NAD + Modulation
    Elena Katsyuba, Johan H. Auwerx · 2018 · Elsevier eBooks
  26. Mechanistic insights into NAD synthase NMNAT chaperoning phosphorylated Tau from pathological aggregation
    Xiaojuan Ma, Jinxia Lu, Yi Zhu, Jingfei Xie, Chong V. Li, Austin Shin, Jiali Qiang, Jiaqi Liu, Shuai Dou, Yi Xiao et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  27. Faculty Opinions recommendation of NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.
    Leonard Μ. Neckers · 2008 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  28. Overexpression of nicotinamide mononucleotide adenyltransferase (nmnat) increases the growth rate, Ca2+ content and cellulase production in Ganoderma lucidum
    Shengli Wang, Jing Dong J Han, Jiale Xia, Yan‐Ru Hu, Liang Shi, Ang Ren, Jing Ke Zhu, Mingwen Zhao · 2020
  29. Nicotinamide-nucleotide adenylyltransferase
    2007 · Springer eBooks
  30. Pyridine (Nicotinamide Adenine) Nucleotide BiosynthesisDe Novo
    Hiroshi Ashihara, Iziar A. Ludwig, Alan Crozier · 2020
  31. Overexpression of nicotinamide mononucleotide adenyltransferase (nmnat) increases growth rate, Ca2+ content and cellulase production in Ganoderma lucidum
    Shengli Wang, Jing Han, Jiale Xia, Yan‐Ru Hu, Liang Shi, Ang Ren, Jing Ke Zhu, Mingwen Zhao · 2019
  32. Disorders of Niacin, NAD, and Pantothenate Metabolism
    Anna Ardissone, Daria Diodato, Ivano Di Meo, Valeria Tiranti · 2022 · Springer eBooks
  33. Arabidopsis thaliana nicotinate mononucleotide adenylyltransferase: unveiling the molecular determinants and evolutionary origin of nicotinic acid mononucleotide recognition
    Leonardo Sorci, Michele Cianci, Carlo Fortunato, Massimiliano Gasparrini, Nadia Raffaelli · 2025 · International Journal of Biological Macromolecules
  34. Pyrimidine and NAD salvage pathways : unexpected allies in the maintenance of genome stability
    Sandra Cunha Silveira · 2018
  35. Accurate and task-agnostic modeling of enzymatic reactions through multimodal relational learning
    Yuansheng Huang, Lanqing Li, Wenjia Qian, Jiahui Yu, Huifeng Zhao, Xiaorui Wang, Odin Zhang, Guangyong Chen, Shukai Gu, Pheng-Ann Heng et al. · 2026 · Acta Pharmaceutica Sinica B
  36. BindingDB Entry 4627: Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD.
    BindingDB · 2011 · UC San Diego
  37. BindingDB Entry 50022689: Assessing the inhibitory effects of some secondary amines, thioureas and 1,3-dimethyluracil conjugates of (-)-cytisine and thermopsine on the RNA-dependent RNA polymerase of SARS-CoV-1 and SARS-CoV-2.
    BindingDB · 2026 · UC San Diego