A Rapid Screen of the Severity of Mild Traumatic Brain Injury
Abstract
This study investigated the sensitivity of information processing, recall and orientation tasks to the presence of mild Traumatic Brain Injury (mTBI). Fifty-six (40 male, 16 female) mTBI patients and 85 (57 male and 28 female) controls with orthopaedic injuries were tested within 24 hr of injury in the Department of Emergency Medicine. mTBI patients answered fewer orientation questions and recalled fewer words in delayed recall than orthopaedic patients. mTBI patients judged fewer sentences in 2 min than orthopaedic controls, and female mTBI patients judged fewer sentences than male mTBI patients. Male mTBI patients correctly recalled fewer words during immediate memory and learning than female mTBI patients and orthopaedic controls. Those mTBI patients with a history of previous head injuries did not perform more poorly than those mTBI patients without previous head injuries. These results indicate that tests of speed of information processing, word learning and orientation questions are sensitive to the acute effects of mTBI.
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Mitochondria extracted from brain, liver, and cerebral arteries of female rodents displayed more efficient oxidative phosphorylation than in males.
“mitochondria extracted from brain, liver, and cerebral arteries of female rodents displayed more efficient oxidative phosphorylation than in males”
From Sex Differences in Traumatic Brain Injury: What We Know and What We Should Know (2019) · cites this paper as [121]
Under physiological conditions, sex-specific differences in mitochondrial respiration, bioenergetics, and reactive oxygen species production have been reported in both human and animal studies.
“Under physiological conditions, sex-specific differences in mitochondrial respiration, bioenergetics, and reactive oxygen species production have been reported in both human and animal studies.”
From Sex Differences in Traumatic Brain Injury: What We Know and What We Should Know (2019) · cites this paper as [121]
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References 17 · Cited by 39
- Authors
- Comerford, V. E., Geffen, G. M., May, C., Medland, S. E., & Geffen, L. B.
- Venue
- Journal of Clinical and Experimental Neuropsychology
- Publisher
- Informa UK Limited
- Published
- 2002-06
- Volume
- 24
- Issue
- 4
- Pages
- 409-419
- ISSN
- 0165-0475 (ISSN-L)
- 1380-3395
- 1744-411X
- OpenAlex
- W2038382506
- Cited by
- 39
- References
- 17
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 1 · 2020: 3 · 2019: 3 · 2017: 1 · 2015: 1 · 2014: 1 · 2013: 4
- FWCI
- 2.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical and Experimental Neuropsychology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Health Sciences › Medicine › Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Keywords
- mild traumatic brain injury, screening, processing speed, word recall, delayed recall, orientation, word learning, sex differences, orthopedic trauma
- MeSH terms
- Acute Disease, Adult, Brain, Brain Injuries, Cognition Disorders, Emergency Medical Services, Female, Humans, Male, Memory Disorders, Neuropsychological Tests, Sampling Studies, Severity of Illness Index, Sex Factors, Task Performance and Analysis, Time Factors
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