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Cited by 44Parasitic Diseases Research and TreatmentParasites and Host InteractionsResearch on Leishmaniasis Studies

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

The use of mebendazole in the treatment of filariases due to Loa loa and Mansonella perstans

Hoegaerden, M. Van, Ivanoff, B., Flocard, F., Salle, A., Chabaud, B.·1987·Annals of Tropical Medicine & Parasitology
DOI 10.1080/00034983.1987.11812120
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Abstract

Patients harbouring Loa loa and/or Mansonella perstans infections, or presenting typical filarial symptomatology, were treated with mebendazole, a drug shown to be efficient in other parasitoses. Of the patients who took the drug during 21 days and provided regular blood samples, 84% showed a significant decrease in their L. loa microfilaraemia and 100% in their M. perstans microfilaraemia, with a concomitant improvement in the clinical manifestations and no side reaction to drug administration. Additionally, the long-lasting effect of the drug (up to day 200 in some cases) may suggest a positive action on the adult worm. Mebendazole may consequently be regarded as a safer alternative to diethylcarbamazine for the treatment of these two parasitoses.

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Research works printed but not linked: 32

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Metadata

Authors
Hoegaerden, M. V., Ivanoff, B., Flocard, F., Salle, A., & Chabaud, B.
Affiliations
Centre International de Recherches Médicales de Franceville (GA)
Venue
Annals of Tropical Medicine & Parasitology
Publisher
Informa UK Limited
Published
1987-01
Volume
81
Issue
3
Pages
275-282
ISSN
  • 0003-4983 (ISSN-L)
  • 1364-8594
DOI
10.1080/00034983.1987.11812120
OpenAlex
W2410075422
Cited by
44
References
1
Citations by year
2026: 1 · 2025: 2 · 2024: 2 · 2023: 3 · 2022: 1 · 2021: 1 · 2019: 1 · 2016: 3 · 2015: 1 · 2014: 1 · 2012: 1
FWCI
1.03
Type
journal article
Language
en
Open access
closed
Locations
  • Annals of Tropical Medicine and Parasitology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
  • Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Research on Leishmaniasis Studies
Keywords
mebendazole, Loa loa, Mansonella perstans, filariasis, microfilaremia, antifilarial treatment, drug safety
MeSH terms
Adolescent, Adult, Animals, Filariasis, Humans, Loiasis, Mansonelliasis, Mebendazole, Microfilariae, Middle Aged

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