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Cited by 243

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DNA fibers by electrospinning

Fang, X., Reneker, D. H.·1997·Journal of Macromolecular Science, Part B

Abstract

Thin fibers of calf thymus Na-DNA were electrospun from aqueous solutions with concentrations from 0.3% to 1.5%. In electrospinning, a high voltage is used to create an electrically charged jet of liquid solution, which dries to leave a polymer fiber. The electrospun DNA fibers have diameters around 50 to 80 nm. The diameter of the electrospun fibers is an order of magnitude or more smaller than that of previously reported fibers. The DNA fibers were observed by optical microscopy, scanning electron microscopy, and transmission electron microscopy. Bead-like structures were observed on many of the fibers. During electrospinning a process called splaying causes the jet to split longitudinally into two smaller jets, which split again, repeatedly, until the very small diameter fibers are formed. The small-diameter fibers are transparent in ordinary 100 kV electron microscopes. Fibers can be spun from samples of DNA as small as 1 mg.

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Crossref · 10.1080/00222349708220422

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Metadata

Authors
Fang, X., & Reneker, D. H.
Venue
Journal of Macromolecular Science, Part B
Published
1997-03
Volume
36
Issue
2
Pages
169-173
ISSN
  • 0022-2348 (ISSN-L)
  • 1525-609X
OpenAlex
W2066505484
Cited by
243
References
1
FWCI
0.74
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: DNA fibers by electrospinning. https://app.cochat.ai/papers/10.1080/00222349708220422
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Fang, X., & Reneker, D. H. (1997). DNA fibers by electrospinning. Journal of Macromolecular Science, Part B. https://doi.org/10.1080/00222349708220422

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