Upper gastrointestinal symptoms in a U.S. national sample of adults with diabetes
Abstract
Background Individuals with diabetes may be particularly susceptible to motility-related upper gastrointestinal (UGI) symptoms such as abdominal pain or discomfort, bloating, early satiety, nausea, and vomiting. We estimated the prevalence of UGI symptoms in a population-based sample of individuals with diabetes and determined whether cases and population controls differed in prevalence of UGI symptoms and in symptom features. Methods Individuals with diabetes (n = 483) and matched controls (n = 422) were recruited from a prior U.S. national health survey for a telephone interview on UGI symptoms. To confirm self-reported diabetes status, cases provided information on clinical management measures. Subjects were asked about UGI symptoms in the month before interview. Affirmative responses to initial questions triggered detailed questions about symptom frequency, timing, duration, and severity. Differences between cases and controls were evaluated. Results Cases not only had a significantly (P Conclusions Upper GI symptoms are common in individuals with diabetes and more prevalent than in controls. The symptoms are non-specific and may reflect disruptions in motility or perception.
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GI symptoms are more frequent in diabetes mellitus than in age- and sex-matched controls.
“Population-based studies demonstrate that GI symptoms are more frequent in diabetes mellitus than in age- and sex-matched controls (Ricci et al., 2000).”
From Autonomic nervous system and gastrointestinal manifestations with an emphasis on gastric dysfunction (2026) · cites this paper as Ricci et al., 2000
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Autonomic nervous system and gastrointestinal manifestations with an emphasis on gastric dysfunction
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- Authors
- J. A. Ricci, R. S.
- Affiliations
- Innovative Medical Research, 1001 Cromwell Bridge Rd., Suite 302, Towson, MD 21286 USA
- Venue
- Scandinavian Journal of Gastroenterology
- Publisher
- Informa UK Limited
- Published
- 2000-01
- Volume
- 35
- Issue
- 2
- Pages
- 152-159
- ISSN
- 0036-5521 (ISSN-L)
- 1502-7708
- OpenAlex
- W2110250323
- Cited by
- 99
- References
- 0
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 1 · 2023: 4 · 2022: 3 · 2021: 3 · 2020: 4 · 2019: 7 · 2018: 6 · 2017: 3 · 2016: 3 · 2015: 1 · 2014: 1 · 2013: 3 · 2012: 6
- FWCI
- 6.75
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Scandinavian Journal of Gastroenterology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- diabetes mellitus, upper gastrointestinal symptoms, gastrointestinal motility, heartburn, bloating, early satiety, nausea, vomiting, abdominal pain, symptom prevalence
- MeSH terms
- Adolescent, Adult, Aged, Female, Gastrointestinal Diseases, Health Surveys, Humans, Male, Middle Aged, United States, Prevalence, Logistic Models, Odds Ratio, Diabetes Complications
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