Cited by 31Optimal Experimental Design MethodsStatistical Methods and Bayesian InferenceSimulation Techniques and Applications

Optimal Design of Blocked and Split-Plot Experiments for Fixed Effects and Variance Component Estimation

Mylona, Kalliopi, Goos, Peter, Jones, Bradley·2014·Technometrics

Abstract

In general, modeling data from blocked and split-plot response surface experiments requires the use of generalized least squares and the estimation of two variance components. The literature on the optimal design of blocked and split-plot response surface experiments, however, focuses entirely on the precise estimation of the fixed factor effects and completely ignores the necessity to estimate the variance components as well. To overcome this problem, we propose a new Bayesian optimal design criterion which focuses on both the variance components and the fixed effects. A novel feature of the criterion is that it incorporates prior information about the variance components through log-normal or beta prior distributions. The resulting designs allow for a more powerful statistical inference than traditional optimal designs. In our algorithm for generating optimal blocked and split-plot designs, we implement efficient quadrature approaches for the numerical approximation of the new optimal design criterion. Supplementary materials for this article are available online.

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Crossref · 10.1080/00401706.2013.818579

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  • The information matrix N in the existing composite criterion of Mylona et al. (2014) depends on the assumed response surface model through P and X, so using its determinant to quantify information on variance components is not model-robust.

    “The main weakness of the composite D-optimality criterion of Mylona et al. (2014) is that the information matrix for the variance components, N, depends on the assumed response surface model through the matrices P and X.”
  • The composite D-optimality criterion of Mylona et al. (2014) generally produces designs with insufficient replicates to allow for pure-error estimation of the variance components.

    “Moreover, generally, the composite Doptimality criterion of Mylona et al. (2014) produces designs with insucient replicates to allow for pure-error estimation of the variance components.”
  • Even the original composite criterion of Mylona et al. (2014) does not lead to inclusion of replicates in the 48-run blocked design.

    “So, even the original composite criterion of Mylona et al. (2014), which takes into account the variance component estimation, does not lead to the inclusion of replicates in the design.”

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Authors
Mylona, K., Goos, P., & Jones, B.
Affiliations
  • University of Southampton (GB)
  • University of Antwerp (BE)
  • SAS Institute (United States) (US)
Venue
Technometrics
Published
2014-04-03
Volume
56
Issue
2
Pages
132-144
ISSN
  • 0040-1706 (ISSN-L)
  • 1537-2723
OpenAlex
W1991273308
Cited by
31
References
2
Citations by year
2025: 3 · 2024: 4 · 2023: 1 · 2022: 5 · 2019: 4 · 2018: 3 · 2017: 4 · 2016: 3 · 2015: 4
FWCI
3.19
Type
journal article
Language
en
Open access
closed
Locations
  • Technometrics (publishedVersion)
  • ePrints Soton (University of Southampton) (acceptedVersion)
Funders
KU Leuven
Topics
  • Social Sciences › Decision Sciences › Management Science and Operations Research › Optimal Experimental Design Methods
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
  • Social Sciences › Decision Sciences › Management Science and Operations Research › Simulation Techniques and Applications
Keywords
optimal experimental design, split-plot design, response surface methodology, variance component estimation, fixed effects estimation, beta prior, generalized least squares, quadrature approximation

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