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Sequential treatments, in which treatments are adapted over time based on the changing clinical status of the patient, are often necessary because treatment effects are heterogeneous across patient...
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In oncology, SMART has been applied to create medication algorithms for prostate cancer.
“For example, SMART has been used in oncology to develop medication algorithms to treat prostate cancer [36,52,53].”
From Introduction to SMART designs for the development of adaptive interventions: with application to weight loss research (2014) · cites this paper as [53]
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References 21 · Cited by 19
- Authors
- Almirall, D., Lizotte, D. J., & Murphy, S. A.
- Affiliations
- University of Michigan (US)
- University of Waterloo (CA)
- Venue
- Journal of the American Statistical Association
- Publisher
- Informa UK Limited
- Published
- 2012-06
- Volume
- 107
- Issue
- 498
- Pages
- 509-512
- ISSN
- 0162-1459 (ISSN-L)
- 1537-274X
- PMC
- PMC3607391
- OpenAlex
- W1935711966
- Cited by
- 19
- References
- 21
- Citations by year
- 2024: 3 · 2023: 1 · 2022: 3 · 2021: 1 · 2020: 1 · 2019: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 4 · 2013: 1
- FWCI
- 1.83
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Journal of the American Statistical Association (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- National Institute of Mental Health (R01MH080015)
- National Institute on Drug Abuse (P50DA010075)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Physical Sciences › Mathematics › Statistics and Probability › Advanced Causal Inference Techniques
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Keywords
- sequential therapy, adaptive therapy, treatment effect heterogeneity, personalized treatment, clinical trials
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