The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Inhibitory effects of Nigella sativa and saffron (crocus sativus) on chemical carcinogenesis in mice
Abstract
Topical application of Nigella sativa and Crocus sativus extracts (common food spices) inhibited two-stage initiation/promotion [dimethylbenz[a]anthracene (DMBA)/croton oil] skin carcinogenesis in mice. A dose of 100 mg/kg body wt of these extracts delayed the onset of papilloma formation and reduced the mean number of papillomas per mouse, respectively. The possibility that these extracts could inhibit the action of 20-methylcholanthrene (MCA)-induced soft tissue sarcomas was evaluated by studying the effect of these extracts on MCA-induced soft tissue sarcomas in albino mice. Intraperitoneal administration of Nigella sativa (100 mg/kg body wt) and oral administration of Crocus sativus (100 mg/kg body wt) 30 days after subcutaneous administration of MCA (745 nmol x 2 days) restricted tumor incidence to 33.3% and 10%, respectively, compared with 100% in MCA-treated controls.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas
Balmain, A., Ramsden, M., Bowden, G. T., & Smith, J. (1984) · Nature · doi:10.1038/307658a0 · Cited by 529
Cited by
Pharmacological and toxicological properties of Nigella sativa
Ali, B. H., & Blunden, G. (2003) · Phytotherapy Research · doi:10.1002/ptr.1309 · Cited by 1,119
Immunomodulatory and therapeutic properties of the Nigella sativa L. seed
Salem, M. L. (2005) · International Immunopharmacology · doi:10.1016/j.intimp.2005.06.008 · Cited by 853
Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice
Hosseinzadeh, H., & Younesi, H. M. (2002) · BMC Pharmacology · doi:10.1186/1471-2210-2-7 · Cited by 606
Thymoquinone and its therapeutic potentials
Darakhshan, S., Bidmeshki Pour, A., Hosseinzadeh Colagar, A., & Sisakhtnezhad, S. (2015) · Pharmacological Research · doi:10.1016/j.phrs.2015.03.011 · Cited by 507
Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials
Abdullaev, F. I., & Espinosa-Aguirre, J. J. (2004) · Cancer Detection and Prevention · doi:10.1016/j.cdp.2004.09.002 · Cited by 434
Metadata
- Authors
- Salomi, M. J., Nair, S. C., & Panikkar, K. R.
- Venue
- Nutrition and Cancer
- Publisher
- Informa UK Limited
- Published
- 1991-01
- Volume
- 16
- Issue
- 1
- Pages
- 67-72
- ISSN
- 0163-5581 (ISSN-L)
- 1532-7914
- OpenAlex
- W1988316941
- Cited by
- 283
- References
- 1
- FWCI
- 0.81
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Inhibitory effects of Nigella sativa and saffron (crocus sativus) on chemical carcinogenesis in mice. https://app.cochat.ai/papers/10.1080/01635589109514142
- The paper
- Salomi, M. J., Nair, S. C., & Panikkar, K. R. (1991). Inhibitory effects of Nigella sativa and saffron (crocus sativus) on chemical carcinogenesis in mice. Nutrition and Cancer. https://doi.org/10.1080/01635589109514142
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
