Cited by 357Bladder and Urothelial Cancer TreatmentsGlobal Cancer Incidence and ScreeningUrinary and Genital Oncology Studies

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The global burden of urinary bladder cancer

Parkin, D. Maxwell·2008·Scandinavian Journal of Urology and Nephrology

DOI 10.1080/03008880802285032

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Abstract

Statistics on the incidence of bladder cancer are particularly hard to interpret, because of changing classification, variations in counting of multiple cancers in the same individual and, most importantly, the variable inclusion of non-invasive cancers in different data sets. Mortality statistics are almost certainly more comparable, but as indirect estimators of disease risk, require some cautious interpretation, because of differing survival between populations, and over time. Cancer of the bladder is estimated to be the ninth most common cause of cancer worldwide (357 000 cases in 2002) and the 13th most numerous cause of death from cancer (145 000 deaths). Rates in males are three to four times those in females. Incidence rates are high in many southern and eastern European countries, in parts of Africa and the Middle East, and in North America. The highest estimated mortality is in Egypt, where rates are more than three times greater than the highest rates in Europe and eight times those in the USA. In the USA, the incidence in whites is higher than in blacks. In general, in Western countries, incidence rates have been rising, but the increase has slowed or stopped in many. Mortality rates are, for the most part, decreasing. Trends are more variable in developing countries. To some extent, the geography and time trends are related to prevalence of known risk factors, especially exposure to tobacco (responsible for almost one-third of bladder cancer deaths) and, in some specific areas, schistosomiasis.

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Authors: Parkin, D. M.
Affiliations: University of Oxford (GB)
Corresponding author: Parkin, D. Maxwell
ORCID: Parkin, D. Maxwell
Venue: Scandinavian Journal of Urology and Nephrology
Publisher: Informa UK Limited
Published: 2008-01-01
Volume: 42
Issue: sup218
Pages: 12-20
ISSN: 0036-5599 (ISSN-L)
1651-2065
DOI: 10.1080/03008880802285032
OpenAlex: W2117705442
Cited by: 357
References: 40
Citations by year: 2026: 2 · 2025: 8 · 2024: 9 · 2023: 8 · 2022: 18 · 2021: 16 · 2020: 10 · 2019: 14 · 2018: 16 · 2017: 29 · 2016: 24 · 2015: 25 · 2014: 31 · 2013: 33 · 2012: 33
FWCI: 4.57
Type: journal article
Language: en
Open access: closed
Locations: Scandinavian Journal of Urology and Nephrology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Surgery › Bladder and Urothelial Cancer Treatments
Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
Health Sciences › Medicine › Surgery › Urinary and Genital Oncology Studies
Keywords: bladder cancer, global burden of disease, cancer incidence, cancer mortality, incidence trends, mortality trends, sex differences, regional variation, tobacco smoke exposure, schistosomiasis, risk factors, non-invasive bladder cancer
MeSH terms: Urinary Bladder Neoplasms, Humans, Morbidity, Risk Factors, Global Health, Survival Rate

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