The meaning in loss protocol: A clinical trial of online grief therapy
Open accessAbstract
For a minority of the bereaved, the loss of a significant other can trigger an overwhelming emotional reaction and impaired functioning across life domains, known as prolonged grief disorder (PGD). Hence, ongoing efforts have been made to refine existing treatments to increase their efficacy and to accommodate the idiosyncrasies of grief reactions. This study presents the results of an open clinical trial of the feasibility and effectiveness of the Meaning in Loss (MIL) protocol in an online format. The brief intervention of 12 to 16 sessions combines constructivist and narrative strategies to explore and work through impediments to meaning reconstruction in loss. The sample included 25 participants diagnosed with PGD who were treated by six therapists. Baseline and post-therapy comparisons showed a significant improvement in all clinical measures (grief symptomatology, depression and general distress) and an increase of meaning making regarding the loss. Meaning making was found to be a prospective mediator of symptomatic improvement in grief across the course of therapy. These findings suggest the effectiveness of the MIL protocol in decreasing grief specific and associated symptomatology and argue for the relevance of further controlled evaluations of its efficacy. Moreover, results confirm previous findings that meaning making is a relevant factor in the evolution of grief reactions, including in the context of psychotherapy.
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Open trials of the meaning reconstruction model with unselected self-referred groups and mourners meeting criteria for PGD have strongly supported the effectiveness of the model.
“Open trials of the model with both unselected self-referred groups experiencing loss and transition (91) and mourners meeting criterial for PGD (92) have strongly supported the effectiveness of the model”
From Ayahuasca-assisted meaning reconstruction therapy for grief: a non-randomized clinical trial protocol (2025) · cites this paper as [92]
Meaning-making prospectively predicts positive adaptation to bereavement.
“added to a growing literature, indicate that meaning-making prospectively predicts positive adaptation to bereavement (88, 92–95).”
From Ayahuasca-assisted meaning reconstruction therapy for grief: a non-randomized clinical trial protocol (2025) · cites this paper as [92]
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References 74 · Cited by 12
- Authors
- Batista, J., Alves, D., Pires, N., Silva, J. R., Mendes, I., Magalhães, C., Rosa, C., Oliveira, J. T., Gonçalves, M. M., & Neimeyer, R. A.
- Affiliations
- University of Minho (PT)
- Centro de Investigação em Serviço Social e Intervenção Social (PT)
- Universidade Portucalense (PT)
- University of Aveiro (PT)
- Portland Institute for Loss and Transition, Portland, Oregon, USA.
- Corresponding author
- Batista, João
- ORCID
- Venue
- Death Studies
- Publisher
- Informa UK Limited
- Published
- 2024-06-28
- Volume
- 49
- Issue
- 1
- Pages
- 8-20
- ISSN
- 0748-1187 (ISSN-L)
- 1091-7683
- OpenAlex
- W4400118934
- Cited by
- 12
- References
- 74
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 3
- FWCI
- 6.00
- Type
- journal article
- Language
- en
- Open access
- green
- repositorio.ismt.pt
- Licence
- other-oa
- Locations
- Death Studies (publishedVersion)
- PubMed (publishedVersion)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, other-oa)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, cc-by-nc-nd)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Grief, Bereavement, and Mental Health
- Social Sciences › Anthropology › Death, Funerary Practices, and Mourning
- Social Sciences › Health › Religion, Spirituality, and Psychology
- Keywords
- prolonged grief disorder, meaning-making, bereavement, constructivist therapy, narrative therapy, depression
- MeSH terms
- Internet-Based Intervention, Adult, Female, Grief, Humans, Male, Middle Aged, Psychotherapy, Treatment Outcome
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