The DOI matches its Crossref record.
Molecular mechanisms of adhesion, colonization, and invasion of group A streptococci
Open accessAbstract
The initial step in establishing a bacterial infection is adhesion of the organism to the epithelium of the host. Group A streptococci use multiple adhesins to attach to host cells and the types of adhesins expressed by a particular strain will determine its tissue specificity. Expression of adhesins is regulated in response to changing environmental and growth conditions. Thus, the array of adhesins expressed by a group A streptococcus will depend on the complement of its adhesin genes and on the environment. Expression of some adhesins may trigger internalization of the streptococci by host cells, which may enable the streptococci to evade antibiotics and to facilitate the penetration of deeper tissues. In this review, we present the different molecular mechanisms of adhesion utilized by group A streptococci and how these interactions lead to colonization and invasion.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Molecular insight into invasive group A streptococcal disease
Cole, J. N., Barnett, T. C., Nizet, V., & Walker, M. J. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2648 · Cited by 377
Streptococcus pyogenes adhesion and colonization
Brouwer, S., Barnett, T. C., Rivera‐Hernandez, T., Rohde, M., & Walker, M. J. (2016) · FEBS Letters · doi:10.1002/1873-3468.12254 · Cited by 113
“Undoubtedly, one of the very first and fundamental stages of GAS pathogenesis is adhesion to and colonization of the epithelium [9-13] (Figure 1).”
BackgroundDahesh, S., Nizet, V., & Cole, J. N. (2012) · Virulence · doi:10.4161/viru.21933 · Cited by 40
Metadata
- Authors
- Courtney, H. S., Hasty, D. L., & Dale, J. B.
- Venue
- Annals of Medicine
- Publisher
- Informa UK Limited
- Published
- 2002-01
- Volume
- 34
- Issue
- 2
- Pages
- 77-87
- ISSN
- 0785-3890 (ISSN-L)
- 1365-2060
- OpenAlex
- W2118675985
- Cited by
- 178
- References
- 0
- FWCI
- 9.66
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Molecular mechanisms of adhesion, colonization, and invasion of group A streptococci. https://app.cochat.ai/papers/10.1080/07853890252953464
- The paper
- Courtney, H. S., Hasty, D. L., & Dale, J. B. (2002). Molecular mechanisms of adhesion, colonization, and invasion of group A streptococci. Annals of Medicine. https://doi.org/10.1080/07853890252953464
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
