The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Nephrotic Syndrome as a Complication of Intravesical BCG Treatment of Transitional Cell Carcinoma of Urinary Bladder
Open accessAbstract
Nephrotic syndrome can be associated with various neoplasms, especially solid tumors and lymphomas. This patient presented with painless hematuria of transitional cell carcinoma of urinary bladder, underwent transurethral resection, but developed recurrence 16 months later. Repeat resection was done and intravesical Bacillus Calmette-Guerin (BCG) injections were started. After six months, the patient developed hypertension and nephrotic syndrome with a biopsy revealing membranous glomerulonephritis, though there was no radiological evidence of tumor. This is the first case of nephrotic syndrome with intravesical BCG instillation in a bladder carcinoma patient.
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“Although corticosteroid therapy effectively mitigates the active inflammatory component, renal function recovery remains predominantly partial [5-8, 13-16].”
From Chronic Granulomatous Interstitial Nephritis Presenting Five Years After Intravesical Bacillus Calmette-Guérin Therapy: A Case Report and Literature Review (2026) · cites this paper as [14]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“This case is remarkable for its exceptionally long and unusual latency period, which generally manifests within days to months in other patients.”
From Chronic Granulomatous Interstitial Nephritis Presenting Five Years After Intravesical Bacillus Calmette-Guérin Therapy: A Case Report and Literature Review (2026) · cites this paper as [14]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Classically, renal complications induced by intravesical BCG instillations--whether glomerular or tubulointerstitial--manifest acutely or subacutely.”
From Chronic Granulomatous Interstitial Nephritis Presenting Five Years After Intravesical Bacillus Calmette-Guérin Therapy: A Case Report and Literature Review (2026) · cites this paper as [14]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Although corticosteroid therapy effectively mitigates the active inflammatory component, renal function recovery remains predominantly partial [5-8, 13-16].”
From Chronic Granulomatous Interstitial Nephritis Presenting Five Years After Intravesical Bacillus Calmette-Guérin Therapy: A Case Report and Literature Review (2026) · cites this paper as [14]
Experimental — accuracy not yet measured
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Citations
Cites
BCG Intravesical Instillations: Recommendations for Side-Effects Management
Rischmann, P., Desgrandchamps, F., Malavaud, B. A., et al. (2000) · European Urology · doi:10.1159/000052381 · Cited by 170
Cure of membranous nephropathy after resection of carcinoma.
Yamauchi, H., Linsey, M. S., Biava, C. G., et al. (1985) · PubMed · Cited by 36
Linear IgA bullous disease in a patient with transitional cell carcinoma of the bladder.
Sa, S., Tschen, J. A., Bean, S. F., et al. (1986) · PubMed · Cited by 33
Renal complications of intravesical bacillus Calmette-Guérin therapy
Modesto, A., Marty, L., Suc, J.-M., Kleinknecht, D., de Frémont, J.-F., Marsepoil, T., & Veyssier, P. (2008) · American Journal of Nephrology · doi:10.1159/000168368 · Cited by 30
Cure of Membranous Nephropathy After Resection of Carcinoma
Yamauchi, H. (1985) · Archives of Internal Medicine · doi:10.1001/archinte.1985.00360110137027 · Cited by 22
Lin, F.-C., Chang, S.-C., Chen, J.-Y., et al. (2002) · The American Journal of the Medical Sciences · doi:10.1097/00000441-200209000-00008 · Cited by 21
Togawa, A., Yamamoto, T., Suzuki, H., et al. (2002) · The Nephron journals/Nephron journals · doi:10.1159/000049047 · Cited by 13
Luyckx, C., Damme, B. V., Vanrenterghem, Y., et al. (2002) · Clinical Nephrology · doi:10.5414/cnp57080 · Cited by 12
Nephrotic Syndrome Associated with Transitional Cell Carcinoma of Urinary Bladder
Reshi, A. R., Mir, S. A., Gangoo, A. A., et al. (1997) · Scandinavian Journal of Urology and Nephrology · doi:10.3109/00365599709070351 · Cited by 12
Spirnak, J. E., Lubke, W. L., Thompson, I. M., et al. (1993) · Urology · doi:10.1016/0090-4295(93)90350-j · Cited by 11
Research works printed but not linked: 2
- Yadav P, 1999, Journal, Indian Academy of Clinical Medicine., 4, 55
- Sekula SA, 1986, Cutis, 38, 354
Cited by
Sorted by citations
Mohammed, A., & Arastu, Z. (2017) · BMC Urology · doi:10.1186/s12894-017-0304-5 · Cited by 20
El Mansouri, M., Benali, H., Ait Elkihal, I., Hamouche, N., Chettati, M., Fadili, W., & Laouad, I. (2026) · Cureus · doi:10.7759/cureus.106712
Metadata
- Authors
- Singh, N. P., Prakash, A., Kubba, S., Ganguli, A., Agarwal, S. K., Dinda, A. K., & Aggarwal, P. N.
- Affiliations
- Maulana Azad Medical College (IN)
- Era's Lucknow Medical College and Hospital (IN)
- Post Graduate Institute of Medical Education and Research (IN)
- Indraprastha Apollo Hospitals (IN)
- All India Institute of Medical Sciences (IN)
- Corresponding author
- Prakash, Anupam
- Venue
- Renal Failure
- Publisher
- Informa UK Limited
- Published
- 2007-01-01
- Volume
- 29
- Issue
- 2
- Pages
- 227-229
- ISSN
- 0886-022X (ISSN-L)
- 1525-6049
- OpenAlex
- W2118731886
- Cited by
- 14
- References
- 14
- Citations by year
- 2026: 1 · 2025: 1 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 1 · 2018: 1 · 2017: 1 · 2014: 1 · 2012: 1
- FWCI
- 0.24
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Renal Failure (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Nephrology › Renal Diseases and Glomerulopathies
- Health Sciences › Medicine › Surgery › Bladder and Urothelial Cancer Treatments
- Health Sciences › Medicine › Urology › Urinary Tract Infections Management
- Keywords
- nephrotic syndrome, BCG immunotherapy, urothelial carcinoma, bladder cancer, membranous nephropathy, hypertension, tumor recurrence, transurethral resection
- MeSH terms
- BCG Vaccine, Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Humans, Male, Middle Aged, Nephrotic Syndrome, Prednisolone, Treatment Outcome
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