Cited by 0Stroke Rehabilitation and RecoveryVirtual Reality Applications and ImpactsTranscranial Magnetic Stimulation Studies

Home-based virtual reality for upper limb stroke rehabilitation: supervised vs. unsupervised approaches – a systematic review with meta-analysis of unsupervised interventions

Karimi, MohammadElias, Aminzadeh, Milad·2026·Disability and Rehabilitation

Abstract

Purpose To evaluate the effectiveness of home-based virtual reality (VR) for upper limb recovery in stroke survivors, specifically distinguishing between supervised and unsupervised approaches.Materials and Methods We searched PubMed, Scopus, and Web of Science for randomized controlled trials (RCTs). Risk of bias was assessed using RoB 2, and certainty of evidence via GRADE. A narrative synthesis included all eligible studies (n = 7), while a meta-analysis focused on a homogeneous subgroup (n = 2) comparing unsupervised home-based VR to unsupervised active controls.Results Seven RCTs (n = 414) were reviewed. The meta-analysis of unsupervised trials (n = 291) showed no significant difference between home-based VR and active control groups (SMD = −0.06; 95% CI: −0.29 to 0.17; p = 0.62; I2 = 0%). Conversely, narrative synthesis indicated that interventions incorporating active remote supervision consistently yielded positive outcomes. The overall certainty of evidence was “Very Low.”Conclusions Unsupervised home-based VR does not appear superior to conventional home exercise. though it serves as a comparable alternative when direct supervision is limited. However, interventions involving therapist supervision show promise. The “human factor” of supervision may be more critical than the technology itself, highlighting the need for future trials to clearly define supervision levels.

Integrity signals

Registry

Crossref · 10.1080/09638288.2026.2673294

Cites

43 of 43 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 6

  1. 10.1007/s40273-018-0715-4 · DOI
  2. The Cochrane Collaboration. Review Manager (RevMan) [Computer program]. Version 5.4. The Cochrane Collaboration; 2020.
  3. Llorens RN, Colomer E, Carolina Alcañiz M. Effectiveness of a home-based telerehabilitation program for the upper extremity in patients with chronic stroke: a randomized controlled trial. Neurorehabil Neural Repair. 2015;29(7):612–621.
  4. 10.1109/RBME.2017.2697241 · DOI
  5. 10.1017/S026646231200008X · DOI
  6. 10.1177/1545968317732663 · DOI

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Authors
Karimi, M., & Aminzadeh, M.
Affiliations
  • Ahvaz Jundishapur University of Medical Sciences (IR)
  • Urmia University of Medical Sciences (IR)
Corresponding author
Karimi, MohammadElias
Venue
Disability and Rehabilitation
Published
2026-05-23
Pages
1-14
ISSN
  • 0963-8288 (ISSN-L)
  • 1464-5165
OpenAlex
W7162200914
Cited by
0
References
43
FWCI
0.00
Type
journal article
Language
en
Open access
closed
Locations
  • Disability and Rehabilitation (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
  • Physical Sciences › Computer Science › Human-Computer Interaction › Virtual Reality Applications and Impacts
  • Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
Keywords
stroke rehabilitation, upper limb recovery, distant supervision, active control, home-based exercise, stroke survivors

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