The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Overview of pharmacological activities of Andrographis paniculata and its major compound andrographolide
Abstract
Andrographis paniculata (A. paniculata) is a medicinal plant traditionally used as anti-inflammation and anti-bacteria herb. Andrographolide, the major active component of A. paniculata, exhibits diverse pharmacological activities, including anti-inflammation, anti-cancer, anti-obesity, anti-diabetes, and other activities. In this article, we comprehensively review the therapeutic potential of A. paniculata and andrographolide focusing on the mechanisms of action and clinical application. We systemically discuss the structure-activity relationship of andrographolide and derivatives. Despite the various pharmacological activities and formula of A. paniculata and andrographolide, we propose further development of more structural derivatives of andrographolide with reduced toxicity and increased therapeutic efficacy is still needed for the clinical application of this ancient mighty herb and its major component.
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HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
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Cited by
Andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach
Enmozhi, S. K., Raja, K., Sebastine, I., & Joseph, J. (2020) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2020.1760136 · Cited by 384
Panossian, A. G., Efferth, T., Shikov, A. N., Pozharitskaya, O. N., Kuchta, K., Mukherjee, P. K., Banerjee, S., Heinrich, M., Wu, W., Guo, D., et al. (2021) · Medicinal Research Reviews · doi:10.1002/med.21743 · Cited by 347
Rizvi, S. A. A., Einstein, G. P., Tulp, O. L., Sainvil, F., & Branly, R. (2022) · Biomolecules · doi:10.3390/biom12101442 · Cited by 181
“It can also control inflammation by regulating the expression of proteins (Dai et al., 2019).”
Background
Metadata
- Authors
- Dai, Y., Chen, S.-R., Chai, L., Zhao, J., Wang, Y., & Wang, Y.
- Venue
- Critical Reviews in Food Science and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2018-09-10
- Volume
- 59
- Issue
- sup1
- Pages
- S17-S29
- ISSN
- 1040-8398 (ISSN-L)
- 1549-7852
- OpenAlex
- W2883130193
- Cited by
- 323
- References
- 73
- FWCI
- 25.24
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dai, Y., Chen, S.-R., Chai, L., Zhao, J., Wang, Y., & Wang, Y. (2019). Overview of pharmacological activities of Andrographis paniculata and its major compound andrographolide. Critical Reviews in Food Science and Nutrition. https://doi.org/10.1080/10408398.2018.1501657
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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