Deep Eutectic Solvents for the Food Industry: Extraction, Processing, Analysis, and Packaging Applications – A Review
Abstract
Food factories seek the application of natural products, green feedstock and eco-friendly processes, which minimally affect the properties of the food item and products. Today, water and conventional polar solvents are used in many areas of food science and technology. As modern chemistry evolves, new green items for building eco-friendly processes are being developed. This is the case of deep eutectic solvents (DESs), named the next generation of green solvents, which can be involved in many food industries. In this review, we timely analyzed the progress on applying DES toward the development of formulations, extraction of target biomolecules, food processing, extraction of undesired molecules, analysis and determination of specific analytes in food samples (heavy metals, pesticides), food microbiology, and synthesis of new packaging materials, among many other applications. For this, the latest developments (over the last 2-3 years) have been discussed emphasizing innovative ideas and outcomes. Relevantly, we discuss the hypothesis and the key features of using DES in the mentioned applications. To some extent, the advantages and limitations of implementing DES in the food industry are also elucidated. Finally, based on the findings of this review, the perspectives, research gaps and potentialities of DESs are stated.
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DES are liquid at room temperature and characterized by non-flammability, low vapor pressure and low melting point, and high chemical and thermal stability.
“In terms of properties, DES are liquid at room temp erature and characterized by non-flammability, low vapor pressure and low melting point, and high chemi cal and thermal stability (12-15,36).”
From Evaluating the green credentials and performance of deep eutectic solvents in the extraction of antibiotics and mycotoxins in foods (2024) · cites this paper as [15]
DES can be designed to target a wide range of low-molecular weight compounds in food and feed by varying the type and molar concentrations of HBAs and HBDs.
“As a result of their unique properties, DES can be designed to target a wide range of low-molecular weight compounds in food and feed by varying the type and molar concentrations of HBAs and HBDs (13-15).”
From Evaluating the green credentials and performance of deep eutectic solvents in the extraction of antibiotics and mycotoxins in foods (2024) · cites this paper as [15]
The main mechanisms through which DES interact with target analytes in different food matrices include hydrogen bonding, π-π, π-cation, ion-dipole force, electrostatic, dipole-dipole, Van der Waals, and hydrophobic interactions.
“In terms of mode of action, hydrogen bonding, π-π, π-cation, ion-dipole force, electrostatic, dipole-dipole, Van der Waals, and hydrophobic inter actions represent the main mechanisms through which DES interact with target analytes in different food and matrices (13-15).”
From Evaluating the green credentials and performance of deep eutectic solvents in the extraction of antibiotics and mycotoxins in foods (2024) · cites this paper as [15]
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References 116 · Cited by 54
- Authors
- Castro-Muñoz, R., Can Karaça, A., Saeed Kharazmi, M., Boczkaj, G., Hernández-Pinto, F. J., Anusha Siddiqui, S., & Jafari, S. M.
- Affiliations
- Department of Sanitary Engineering, Faculty of Civil and Environmental Engineering, Gdansk University of Technology, Gdansk, Poland
- Department Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, Istanbul, Turkey
- Faculty of Medicine, University of California, Riverside, USA
- Gdańsk University of Technology (PL)
- Tecnológico de Monterrey (MX)
- Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Straubing, Germany
- Hebei Agricultural University (CN)
- Venue
- Critical Reviews in Food Science and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2023-07-03
- Volume
- 64
- Issue
- 30
- Pages
- 10970-10986
- ISSN
- 1040-8398 (ISSN-L)
- 1549-7852
- OpenAlex
- W4382918964
- Cited by
- 54
- References
- 116
- Citations by year
- 2026: 13 · 2025: 27 · 2024: 11 · 2023: 3
- FWCI
- 0.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Critical Reviews in Food Science and Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Istanbul Technical University Academic Open Archive (Istanbul Technical University) (submittedVersion)
- Topics
- Physical Sciences › Chemical Engineering › Catalysis › Ionic liquids properties and applications
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
- Physical Sciences › Chemical Engineering › Filtration and Separation › Chemical and Physical Properties in Aqueous Solutions
- Keywords
- deep eutectic solvents, green solvents, food industry applications, food extraction, food processing, food analysis, heavy metal determination, pesticide residues, food microbiology, food packaging materials, green chemistry
- MeSH terms
- Deep Eutectic Solvents, Food Handling, Solvents, Food Packaging, Food Industry
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