Significance of cigarette smoking among youths with bipolar disorder
Open accessAbstract
Cigarette smoking among adults with bipolar disorder (BP) correlates with psychosis, substance use disorders (SUD), and suicidality. Little is known regarding smoking among youths with BP. Youths with BP (n = 441) were divided into three smoking groups: Never, Ever, and Daily. Twenty-five percent reported any smoking (11% daily, 14% ever). Ever and Daily subjects had significantly greater lifetime prevalence of suicide attempts, physical abuse, conduct disorder, and SUD compared to Never subjects. Daily heavy smokers had greater prevalence of SUD and suicide attempts, and worse depression versus daily light smokers. Smoking among youths with BP is independently associated with suicide attempts and SUD.
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Compared to adolescents with bipolar disorder who never smoked, smoking status was associated with a greater prevalence of bipolar I disorder, earlier onset of bipolar disorder, higher lifetime prevalence of physical and sexual abuse, suicide attempts, conduct disorder, and other substance use disorders.
“Compared to those adolescents with BD who never smoked, smoking status was associated with a greater prevalence of BD-I, earlier onset of BD, higher lifetime prevalence of physical and sexual abuse as well as suicide attempts, conduct disorder, and other substance use disorders (SUD).”
From The detrimental effects of smoking on the course and outcome in adults with bipolar disorder—A narrative review (2023) · cites this paper as [40]
The Results (Clinical characteristics) support higher prevalence of suicide attempts, physical abuse, conduct disorder, and substance use disorders in the Ever and Daily groups versus Never, and higher sexual abuse and bipolar I prevalence in the Ever group. But the onset claim is reversed: the Never group had a significantly younger age of bipolar-disorder onset than both smoking groups. (LLM, conf=0.90)
Experimental — accuracy not yet measuredPrevious psychiatric hospitalizations were significantly more frequent among daily smokers compared with those who never smoked in adolescents with bipolar disorder.
“In addition, previous psychiatric hospitalizations were significantly more frequent among daily smokers vs. those who never smoked (40).”
From The detrimental effects of smoking on the course and outcome in adults with bipolar disorder—A narrative review (2023) · cites this paper as [40]
In the Course and Outcome of Bipolar Youth study, 25% of adolescents with bipolar disorder had ever smoked, 11% smoked daily, and half of the daily smokers were heavy smokers (≥10 cigarettes per day).
“Twenty-five percent of the study participants had ever smoked, with 11 % daily, and half of them had been heavy smokers (≥10 cigarettes per day).”
From The detrimental effects of smoking on the course and outcome in adults with bipolar disorder—A narrative review (2023) · cites this paper as [40]
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References 38 · Cited by 44
- Authors
- Goldstein, B. I., Birmaher, B., Axelson, D. A., Goldstein, T. R., Esposito‐Smythers, C., Strober, M. A., Hunt, J., Leonard, H., Gill, M. K., Iyengar, S., Grimm, C., Yang, M., Ryan, N. D., & Keller, M. B.
- Affiliations
- University of Pittsburgh (US)
- University of California, Los Angeles (US)
- Brown University (US)
- Corresponding author
- Goldstein, Benjamin I.
- ORCID
- Venue
- The American Journal on Addictions
- Publisher
- Wiley
- Published
- 2008-09-10
- Volume
- 17
- Issue
- 5
- Pages
- 364-371
- ISSN
- 1055-0496 (ISSN-L)
- 1521-0391
- PMC
- PMC2905883
- OpenAlex
- W2118047217
- Cited by
- 44
- References
- 38
- Citations by year
- 2023: 2 · 2022: 2 · 2021: 1 · 2020: 2 · 2018: 2 · 2017: 1 · 2016: 2 · 2015: 9 · 2014: 3 · 2013: 6 · 2012: 6
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal on Addictions (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH059929, MH59691, R01MH059977, R01MH112543, R01MH059691, MH59977, MH-59929)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- cigarette smoking, bipolar disorder, adolescents, suicide attempts, substance use disorders, conduct disorder, physical abuse, depression, smoking prevalence, daily smoking
- MeSH terms
- Adolescent, Mental Disorders, Bipolar Disorder, Child, Female, Humans, Male, Psychotic Disorders, Surveys and Questionnaires, Smoking, Suicide, Attempted, Prevalence, Substance-Related Disorders, Diagnostic and Statistical Manual of Mental Disorders
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