CoChat
Sign Up
Cited by 254Optimal Experimental Design MethodsStatistical Methods in Clinical TrialsStatistical Methods and Applications

The DOI matches its Crossref record.

Design of Experiments: Concept and Applications of Plackett Burman Design

Vanaja, K., Shobha Rani, R.H.·2007·Clinical Research and Regulatory Affairs
DOI 10.1080/10601330701220520
Open this paper in CoChat — free account

Abstract

Application of statistics has broadened far beyond its origin to various areas of research and one among them is the design of experiments. Design of experiments gathers the maximum amount of information in the lowest number of analyses. In order to optimize a process and maintain repeatability, screening designs are performed. A two-level, mathematically derived multiples of four screening design, popularly known as Plackett-Burman screening design, is thoroughly reviewed in this paper. Application of this design in various areas of research such as formulation development and analytical development has also been focused to explore its potential in screening unbiased estimates of all main effects in the smallest design.

Overview

Integrity signals

Registry

Crossref · 10.1080/10601330701220520

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 46

  1. Jacquez JA, 1998, Pergamon, 3358, 259
  2. 10.1016/j.chroma.2004.06.010 · DOI
  3. 10.1201/b14760-120 · DOI
  4. 10.1201/b14760-126 · DOI
  5. 10.1016/S0378-3758(02)00216-1 · DOI
  6. Wass JA, 1997, IVD Technology Magazine
  7. 10.1016/S0003-2670(99)00113-0 · DOI
  8. 10.1093/biomet/33.4.305 · DOI · Paper page
  9. 10.1016/S0731-7085(01)00419-8 · DOI
  10. 10.1016/S0003-2670(00)80490-0 · DOI
  11. 10.1016/S0731-7085(97)00196-9 · DOI
  12. 10.1016/0003-2670(95)00221-K · DOI
  13. 10.1016/j.aca.2005.01.051 · DOI
  14. 10.1016/j.jpba.2004.11.033 · DOI
  15. Vikas R, 2005, J. Pharm Pharmaceut Sci, 8, 10
  16. 10.1016/S0031-6865(97)00052-6 · DOI
  17. 10.1016/S0378-5173(99)00324-5 · DOI
  18. 10.1016/S0378-5173(02)00037-6 · DOI
  19. Siobanda W, 2004, AAPS PharmSciTech, 5, 1
  20. 10.1016/S0731-7085(03)00032-3 · DOI
  21. Zaghloul AA, 2001, Pharmazie, 56, 321
  22. 10.3109/10837459609031429 · DOI
  23. 10.1081/CRP-200050003 · DOI
  24. 10.1023/B:PHAM.0000019309.23212.d3 · DOI
  25. Rodriguez JC, 2005, J AOAC Int, 88, 1148, 10.1093/jaoac/88.4.1148 · DOI
  26. 10.1016/0378-5173(93)90136-4 · DOI
  27. 10.1081/DDC-100000127 · DOI
  28. Srisagul S, 2004, Naresuan University Journal, 12, 1
  29. Donald DH, 2005, Drug Stability, Principles and Practices 3d, 329
  30. 10.1016/j.chroma.2005.03.016 · DOI
  31. 10.1016/S0021-9673(99)01303-5 · DOI
  32. 10.1007/BF02269627 · DOI
  33. Predrag S, J Serb Chem Soc, 70, 979
  34. 10.1016/j.aca.2006.01.101 · DOI
  35. 10.1016/S0731-7085(02)00640-4 · DOI
  36. 10.1002/bmc.1130030508 · DOI
  37. 10.1016/S0021-9673(03)01324-4 · DOI
  38. 10.1016/0003-2670(95)00349-5 · DOI
  39. 10.1016/S0021-9673(03)01324-4 · DOI
  40. 10.1016/j.chroma.2005.09.005 · DOI
  41. 10.1016/S0021-9673(02)00549-6 · DOI
  42. 10.1016/j.chroma.2004.06.010 · DOI
  43. 10.1016/j.chroma.2004.01.046 · DOI
  44. 10.1016/S0021-9673(00)01036-0 · DOI
  45. 10.1016/j.jchromb.2004.07.016 · DOI
  46. 10.1016/S0021-9673(00)01036-0 · DOI

Cited by

Sorted by citations

Metadata

Authors
Vanaja, K., & Shobha Rani, R. H.
Affiliations
Al-Ameen College of Pharmacy (IN)
ORCID
Vanaja, K.
Venue
Clinical Research and Regulatory Affairs
Publisher
Informa UK Limited
Published
2007-01
Volume
24
Issue
1
Pages
1-23
ISSN
  • 1060-1333 (ISSN-L)
  • 1532-2521
DOI
10.1080/10601330701220520
OpenAlex
W1980086200
Cited by
254
References
0
Citations by year
2026: 19 · 2025: 35 · 2024: 42 · 2023: 35 · 2022: 30 · 2021: 22 · 2020: 23 · 2019: 16 · 2018: 9 · 2017: 6 · 2016: 1 · 2015: 5 · 2013: 3 · 2012: 2
FWCI
1.44
Type
journal article
Language
en
Open access
closed
Locations
Clinical Research and Regulatory Affairs (publishedVersion)
Funders
  • U.S. Department of Energy
  • Indian Council of Medical Research
Topics
  • Social Sciences › Decision Sciences › Management Science and Operations Research › Optimal Experimental Design Methods
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Applications
Keywords
Plackett-Burman design, screening designs, two-level factorial designs, main effects estimation, process optimization, formulation development, analytical method development, experimental design

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review