The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.
Role of oxidative stress in nanoparticles toxicity
Abstract
Oxidative stress plays a critical role in nanotoxicity. Various types of nanoparticles are known to induce oxidative stress by generating intracellular reactive oxygen species (ROS). Cellular uptake of nanoparticles and intracellular metal ion release are important factors for intracellular ROS generation. Besides, ROS generation can result from interactions of nanoparticles and cells that lead to mitochondrial dysfunction. In vivo, nanoparticles induce the secretion of cytokines, which, in turn, induce secondary oxidative stress via generation of ROS and free radicals. However, not all nanoparticles induce oxidative stress. Intracellular ROS generation by nanoparticles depends on their physical and chemical properties, such as the crystalline phase, adsorption ability, and solubility. Even if the particle size is nanoscale (1–100 nm), physically and chemically inactive particles do not induce oxidative stress. Thus, the particle size is not a direct influencing factor in nanoparticle-induced oxidative stress.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Helical microtubules of graphitic carbon
Iijima, S. (1991) · Nature · doi:10.1038/354056a0 · Cited by 43,098
Electrochemical Photolysis of Water at a Semiconductor Electrode
FUJISHIMA, A., & HONDA, K. (1972) · Nature · doi:10.1038/238037a0 · Cited by 34,169
Carbon Nanotubes: Present and Future Commercial Applications
De Volder, M. F. L., Tawfick, S. H., Baughman, R. H., & Hart, A. J. (2013) · Science · doi:10.1126/science.1222453 · Cited by 5,587
Metals, Toxicity and Oxidative Stress
Valko, M., Morris, H., & Cronin, M. (2005) · Current Medicinal Chemistry · doi:10.2174/0929867053764635 · Cited by 5,018
Cedervall, T., Lynch, I., Lindman, S., Berggård, T., Thulin, E., Nilsson, H., Dawson, K. A., & Linse, S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608582104 · Cited by 3,281
Del Rio, D., Stewart, A. J., & Pellegrini, N. (2005) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2005.05.003 · Cited by 2,721
Poland, C. A., Duffin, R., Kinloch, I., Maynard, A., Wallace, W. A. H., Seaton, A., Stone, V., Brown, S., MacNee, W., & Donaldson, K. (2008) · Nature Nanotechnology · doi:10.1038/nnano.2008.111 · Cited by 2,645
Xia, T., Kovochich, M., Liong, M., Mädler, L., Gilbert, B., Shi, H., Yeh, J. I., Zink, J. I., & Nel, A. E. (2008) · ACS Nano · doi:10.1021/nn800511k · Cited by 2,469
8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis
VALAVANIDIS, A., VLACHOGIANNI, T., & FIOTAKIS, C. (2009) · Journal of Environmental Science and Health, Part C · doi:10.1080/10590500902885684 · Cited by 1,978
Xia, T., Kovochich, M., Brant, J., Hotze, M., Sempf, J., Oberley, T., Sioutas, C., Yeh, J. I., Wiesner, M. R., & Nel, A. E. (2006) · Nano Letters · doi:10.1021/nl061025k · Cited by 1,918
Metadata
- Authors
- Horie, M., & Tabei, Y.
- Venue
- Free Radical Research
- Publisher
- Informa UK Limited
- Published
- 2020-12-18
- Volume
- 55
- Issue
- 4
- Pages
- 331-342
- ISSN
- 1029-2470 (ISSN-L)
- 1071-5762
- OpenAlex
- W3107733841
- Cited by
- 253
- References
- 101
- FWCI
- 8.20
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Role of oxidative stress in nanoparticles toxicity. https://app.cochat.ai/papers/10.1080/10715762.2020.1859108
- The paper
- Horie, M., & Tabei, Y. (2021). Role of oxidative stress in nanoparticles toxicity. Free Radical Research. https://doi.org/10.1080/10715762.2020.1859108
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
