Preparative Isolation of Mangiferin from Anemarrhena asphodeloides Rhizomes by Centrifugal Partition Chromatography
Abstract
Mangiferin was separated from rhizomes of Anemarrhena asphodeloides extract using centrifugal partition chromatography (CPC) with a two‐phase solvent system composed of ethyl acetate‐isopropanol‐water (3∶2∶5, v/v). Mangiferin (22.5 mg) was successfully isolated from methanolic extracts (957 mg) in only one step, and the purity of isolated compound was determined to be over 95% by HPLC analysis. The structure of mangiferin was identified by 1H, 13C NMR and ESI‐MS spectral data analysis.
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Mangiferin has prominent antibacterial and antiviral effects.
“In addition to its antioxidative, antidiabetic and antitumor properties, the antibacterial and antiviral effects of mangiferin are also prominent (110).”
From Mangiferin: An effective therapeutic agent against several disorders (Review) (2018) · cites this paper as [110]
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References 11 · Cited by 30
- Authors
- Young Kim, C., Ahn, M., & Kim, J.
- Affiliations
- College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea
- Seoul National University (KR)
- Corresponding author
- Kim, Jinwoong
- Venue
- Journal of Liquid Chromatography & Related Technologies
- Publisher
- Informa UK Limited
- Published
- 2006-01
- Volume
- 29
- Issue
- 6
- Pages
- 869-875
- ISSN
- 1082-6076 (ISSN-L)
- 1520-572X
- OpenAlex
- W1993368801
- Cited by
- 30
- References
- 11
- Citations by year
- 2026: 2 · 2025: 1 · 2023: 2 · 2019: 1 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 3 · 2014: 3 · 2013: 2 · 2012: 2
- FWCI
- 1.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Liquid Chromatography & Related Technologies (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Analytical Chemistry › Chromatography in Natural Products
- Health Sciences › Medicine › Complementary and alternative medicine › Mangiferin and Mango Extracts
- Health Sciences › Medicine › Complementary and alternative medicine › Traditional Chinese Medicine Analysis
- Keywords
- mangiferin, Anemarrhena asphodeloides, rhizome, centrifugal partition chromatography, preparative isolation, methanol extract, structural identification
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