Toward minimally disruptive management of symptomatic endometriosis: Reducing low-value care and the burden of treatment
Open accessAbstract
Endometriosis is a chronic gynecological disorder afflicting reproductive-age women. Different pathogenic hypotheses have been formulated to explain the development of this disease. According to a ...
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One-third of women with endometriosis do not respond to OCPs or progestogens because of progesterone resistance.
“in one-third of women due to progesterone resistance”
From Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review (2021) · cites this paper as [61]
OCPs have no beneficial effect on non-menstrual pelvic pain and dyspareunia.
“There was, however, a lack of any beneficial effect of OCPs on non-menstrual pelvic pain and dyspareunia”
From Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review (2021) · cites this paper as [61]
OCPs can play an important role in the management of endometriosis, as two-thirds of women with symptomatic endometriosis respond to estroprogestins.
“these authors concluded that OCPs can play an important role in the management of endometriosis, as two-thirds of women with symptomatic endometriosis respond to estroprogestins.”
From Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review (2021) · cites this paper as [61]
The risk of venous or arterial thrombosis with OCPs is not negligible.
“the risk of venous or arterial thrombosis is not negligible [54,55,56,57,58,59,60,61,62,63,64,65,66,67].”
From Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review (2021) · cites this paper as [61]
33% of patients given estroprogestins and/or progestins do not respond to therapy.
“33% of patients given estroprogestins and/or progestins do not respond to therapy.”
From Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review (2021) · cites this paper as [61]
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References 18 · Cited by 24
- Authors
- Vercellini, P., Frattaruolo, M. P., & Buggio, L.
- Affiliations
- University of Milan (IT)
- Corresponding author
- Vercellini, Paolo
- Venue
- Expert Review of Pharmacoeconomics & Outcomes Research
- Publisher
- Informa UK Limited
- Published
- 2017-12-06
- Volume
- 18
- Issue
- 1
- Pages
- 1-4
- ISSN
- 1473-7167 (ISSN-L)
- 1744-8379
- OpenAlex
- W2772900985
- Cited by
- 24
- References
- 18
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 2 · 2021: 5 · 2020: 1 · 2019: 8 · 2018: 4
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Expert Review of Pharmacoeconomics & Outcomes Research (publishedVersion)
- PubMed (publishedVersion)
- Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (submittedVersion, other-oa)
- Funders
- Ministero dell’Istruzione, dell’Università e della Ricerca - devolved to Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Health Professions › General Health Professions › Healthcare cost, quality, practices
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Keywords
- endometriosis, low-value care, treatment burden, endometriosis pathogenesis, gynecological diseases, women's health
- MeSH terms
- Adolescent, Adult, Endometriosis, Female, Humans, Middle Aged, Quality of Life, Cost of Illness, Young Adult
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