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Maternal and obstetrical predictors of sudden infant death syndrome (SIDS)
Abstract
Objective Public Health initiatives, such as the "Safe to Sleep" campaign, have traditionally targeted infants' risk factors for the prevention of Sudden Infant Death Syndrome (SIDS). However, controversy remains regarding maternal and obstetrical risk factors for SIDS. In our study, we sought out to determine both modifiable and non-modifiable obstetrical and maternal risk factors associated with SIDS. Methods We conducted a population-based cohort study using the CDC's Linked Birth-Infant Death data from the United States for the year 2010. The impact of several obstetrical and maternal risk factors on the risk of overall infant mortality and SIDS was estimated using unconditional regression analysis, adjusting for relevant confounders. Results Our cohort consisted of 4,007,105 deliveries and 24,174 infant deaths during the first year of life, of which 1991 (8.2%) were due to SIDS. Prominent risk factors for SIDS included (OR [95% CI]): black race, 1.89 [1.68-2.13]; maternal smoking, 3.56 [3.18-3.99]; maternal chronic hypertension, 1.73 [1.21-2.48]; gestational hypertension, 1.51 [1.23-1.87]; premature birth <37 weeks, 2.16 [1.82-2.55]; IUGR, 2.46 [2.14-2.82]; and being a twin, 1.81 [1.43-2.29], p < 0.0001. Relative to a cohort of infants who died of other causes, risk factors with a predilection for SIDS were maternal smoking, 2.48 [2.16-2.83] and being a twin, 1.52 [1.21-1.91], p < 0.0001. Conclusions for practice: While certain socio-demographic and gestational character…
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“However, despite small numbers, the estimates and confidence intervals are in agreement with international studies on smoking, post neonatal mortality, SIDS and SUID.19–22”
From Association of maternal snuff use and smoking with Sudden Infant Death Syndrome: a national register study (2023) · cites this paper as [19]
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Cited by
Sorted by citations
Maternal Smoking Before and During Pregnancy and the Risk of Sudden Unexpected Infant Death
Anderson, T. M., Lavista Ferres, J. M., Ren, S. Y., Moon, R. Y., Goldstein, R. D., Ramirez, J.-M., & Mitchell, E. A. (2019) · Pediatrics · doi:10.1542/peds.2018-3325 · Cited by 201
Gunnerbeck, A., Lundholm, C., Rhedin, S., Mitha, A., Chen, R., D’Onofrio, B. M., & Almqvist, C. (2023) · Pediatric Research · doi:10.1038/s41390-022-02463-4 · Cited by 27
Metadata
- Authors
- Friedmann, I., Dahdouh, E. M., Kugler, P., Mimran, G., & Balayla, J.
- Venue
- The Journal of Maternal-Fetal & Neonatal Medicine
- Publisher
- Informa UK Limited
- Published
- 2016-11-24
- Volume
- 30
- Issue
- 19
- Pages
- 2315-2323
- ISSN
- 1476-7058
- 1476-4954
- Cited by
- 21
- References
- 1
- Language
- en
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- Friedmann, I., Dahdouh, E. M., Kugler, P., Mimran, G., & Balayla, J. (2017). Maternal and obstetrical predictors of sudden infant death syndrome (SIDS). The Journal of Maternal-Fetal & Neonatal Medicine. https://doi.org/10.1080/14767058.2016.1247265
