RETRACTED ARTICLE: Omega-3 fatty acids plus vitamin for women with gestational diabetes or prediabetes: a meta-analysis of randomized controlled studies
Abstract
INTRODUCTION: Omega-3 fatty acids plus vitamin (e.g. vitamin D and E) may be beneficial to treat gestational diabetes mellitus (GDM), and we aimed to study the influence of omega-3 fatty acids plus vitamin versus placebo on the treatment efficacy of GDM. METHODS: We searched the databases including PubMed, Embase, and the Cochrane Central Register of Controlled Trials, and randomized controlled trials (RCTs) assessing the influence of omega-3 fatty acids and vitamins combination supplementation versus placebo on metabolic status of GDM were included. RESULTS: < .00001). CONCLUSIONS: The supplementation of omega-3 fatty acids in combination with vitamin D or E can improve glycemic control, alleviate oxidative stress, and reduce triglycerides, but had no effects on total cholesterol, preterm delivery or macrosomia > 4000 g in women with GDM or prediabetes.
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Omega-3 fatty acids (with vitamin D or E) lower fasting glucose and insulin resistance among women with GDM compared to a control group.
“A meta-analysis of randomised controlled trials showed that omega-3 fatty acids (with vitamin D or E) lowered fasting glucose and insulin resistance among women with GDM compared to a control group [115].”
From Medical Nutrition Therapy for Women with Gestational Diabetes: Current Practice and Future Perspectives (2025) · cites this paper as [115]
Cites
Preservation of β-Cell Function: The Key to Diabetes Prevention
DeFronzo, R. A., & Abdul-Ghani, M. A. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-0246 · Cited by 247 · see citing works
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Cheong, L., Law, L. S.-C., Tan, L. Y. L., Amal, A. A.-A., Khoo, C. M., & Eng, P. C. (2025) · Nutrients · doi:10.3390/nu17071210 · Cited by 14 · see citing works
- Authors
- Jiang, L., Gao, C., Yan, P., Chen, P., Jiang, C., Xu, Y., & Chen, M.
- Affiliations
- Affiliated Hospital of Southwest Medical University (CN)
- Corresponding author
- Chen, Muhu
- Venue
- The Journal of Maternal-Fetal & Neonatal Medicine
- Publisher
- Informa UK Limited
- Published
- 2020-09-23
- Volume
- 35
- Issue
- 16
- Pages
- 3135-3142
- ISSN
- 1476-4954 (ISSN-L)
- 1476-7058
- OpenAlex
- W3088062730
- Cited by
- 16
- References
- 1
- Citations by year
- 2025: 4 · 2024: 3 · 2023: 2 · 2022: 4 · 2021: 3
- FWCI
- 0.26
- Type
- journal article
- Language
- en
- Status
- Retracted
- Update notices
- retraction (2025-05-08)
- Open access
- closed
- Locations
- The Journal of Maternal-Fetal & Neonatal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Keywords
- omega-3 fatty acids, vitamin D, vitamin E, gestational diabetes mellitus, prediabetes, dietary supplementation, glycemic control, oxidative stress, triglycerides, preterm birth, macrosomia, total cholesterol
- MeSH terms
- Blood Glucose, Female, Fetal Macrosomia, Humans, Infant, Newborn, Cholesterol, LDL, Prediabetic State, Pregnancy, Triglycerides, Vitamin D, Vitamin E, Vitamins, Fatty Acids, Omega-3, Diabetes, Gestational, Dietary Supplements, Premature Birth
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