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Optimization of ultrasound-assisted extraction of phenolic compounds from Sesamum indicum
Abstract
Effective extraction of phyto-biomolecules insures retaining maximum functionality along with higher recovery. In this study, ultrasound-solvent assisted extraction (USAE) was employed for optimal extraction of phyto-biomolecules from Sesamum indicum (sesame) leaves using the approach of Response Surface Methodology (RSM). The optimized condition of 200 W power, 59% methanol concentration with 1:14 g/mL solid-liquid ratio and 15 min of extraction time yielded 367.39 ± 1.85 mg GAE/100 g of total phenolic content, 96.72 ± 3.27% of free radical scavenging activity and 81.20 ± 2.87% of iron chelating activity respectively. The extract consist of essential phytocomponents like gallic acid, chlorogenic acid, and quercetin with lipid peroxidation activities of >50% over incubation time of 48 h. Also, showed antimicrobial activity against various Gram's negative and positive food borne pathogens. The results of this study implied the importance of USAE for effective and optimum recovery of phyto-biomolecules from Sesame leaves with retained functional properties.
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“Sesamol, a constituent of A. graveolens, has been shown to possess significant activities including the scavenging of free radicals, the chelation of iron, and the inhibition of lipid peroxidation46.”
From Synergistic and antagonistic contributions of main components to the bioactivity profile of Anethum graveolens extract (2025) · cites this paper as [46]
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Research works printed but not linked: 9
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- 10.1016/j.nutres.2005.05.007 · DOI
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- 10.1080/10408398.2012.667849 · DOI
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Cited by
Kesti Usta, S., Yalçın, E., & Çavuşoğlu, K. (2025) · Scientific Reports · doi:10.1038/s41598-025-07297-8 · Cited by 10
Metadata
- Authors
- Sarma, L., Chakraborty, S., Jyoti Das, M., & Kumar Duary, R.
- Venue
- Natural Product Research
- Publisher
- Informa UK Limited
- Published
- 2019-01-24
- Volume
- 34
- Issue
- 13
- Pages
- 1931-1936
- ISSN
- 1478-6419
- 1478-6427
- Cited by
- 16
- References
- 0
- Language
- en
- Funders
- Department of Science & Technology (SB/YS/LS-30/)
- Science and Engineering Research Board.
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