Relative safety and quality of various dietary supplement products U.S. Service Members ask about
Abstract
CONTEXT: The purpose of this project was to determine types of dietary supplement products U.S. Service Members frequently ask about and identify risks associated with select products that consumers should be aware of when considering their use. METHODS: Forty-one dietary supplement products frequently asked about through the Operation Supplement Safety's (OPSS.org) Ask-the-Expert portal were selected. Product analysis was performed to verify whether select products were accurately labeled and to identify any risky ingredients contained in these products. Operation Supplement Safety Risk Assessment Scorecard criteria were additionally used as a screening tool to assess a product's relative safety potential. RESULTS: Among the select dietary supplements, 12 (29.3%) were marketed as pre-workout products; 14 (34.1%) for weight loss; four (9.8%) for male enhancement/testosterone boosters; and 11 (26.8%) as body building supplements. Eleven (26.8%) products had accurate labels; only eight of these had accurate labels plus no risky ingredients listed on the labels. Twenty-six (63.4%) products were misbranded; 10 (24.4%) were adulterated, and six (14.6%) were both misbranded and adulterated. Risky ingredients appeared on 23 (56%) of all product labels. Eight of these 23 products also had additional risky ingredients not listed on the labels but detected through analysis. According to the Scorecard based on label claims, 35 (85.4%) received a rating of "no-go/risky". CONCLUSIONS: U.S. Service Members and the public at large should be aware that dietary supplements may contain risky ingredients and know how to identify ingredients on the label to evaluate potential risk.
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Several studies of the accuracy of dietary supplement labeling have found that many of the products analyzed contained significantly lower amounts of the specific ingredient or additional, possibly risky, ingredients that were not declared on the supplement label [29,32,33,76-81].
“Several studies of the accuracy of dietary supplement labeling have found that many of the products analyzed contained significantly lower amounts of the specific ingredient or additional, possibly risky, ingredients that were not declared on the supplement label [29,32,33,76–81].”
From How reliable is the labeling of a commercial phytosteroid product? A 12-week randomized double-blind training study (2025) · cites this paper as [79]
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References 33 · Cited by 24
- Authors
- Crawford, C., Walter, A. R., Avula, B., Lindsey, A. T., Hunter, A. M., Ikhlas, A. K., & Deuster, P. A.
- Affiliations
- Henry M. Jackson Foundation (US)
- University of Mississippi (US)
- Uniformed Services University of the Health Sciences (US)
- Corresponding author
- Crawford, Cindy
- Venue
- Clinical Toxicology
- Publisher
- Informa UK Limited
- Published
- 2022-02-14
- Volume
- 60
- Issue
- 6
- Pages
- 737-744
- ISSN
- 0009-9309 (ISSN-L)
- 1556-3650
- 1556-9519
- OpenAlex
- W4212787631
- Cited by
- 24
- References
- 33
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 4 · 2023: 13 · 2022: 2
- FWCI
- 5.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Toxicology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Consortium for Health and Military Performance and Operation Supplement Safety (HU0001-18-2-0099)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pharmaceutical Quality and Counterfeiting
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Keywords
- dietary supplements, supplement safety, pre-workout supplements, weight loss supplements, misbranding, adulteration, label accuracy, consumer health information
- MeSH terms
- Humans, Military Personnel, Product Labeling, Dietary Supplements
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