Combining Pharmacotherapy with Cognitive‐Behavioral Interventions for Obsessive‐Compulsive Disorder
Abstract
This paper reviews the evidence-based literature concerning the efficacy and effectiveness of cognitive behavior therapy (CBT), drug treatment and their combination for obsessive compulsive disorder (OCD). After a brief outline of the seminal studies, the state of the art is presented with reference to the consensual recommendations proposed in the last 10 years. Management of OCD rests on potent selective serotonin reuptake inhibitors and CBT, used separately, sequentially, or concurrently. A hierarchical model for clinical decision-making is reported. With greater severity of OCD, it is recommended to add medications. However, the response rate is still too low in many patients, and some patients remain refractory to any kind of treatment. This stresses the importance of joint efforts of psychological and biological teams to develop new treatments.
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Près de 40% des patients atteints de TOC refusent l'exposition, s'avèrent résistants ou rechutent.
“Cependant, près de 40% des patients refusent l’exposition, s’avèrent résistants ou rechutent (Cottraux, Bouvard et Milliery, 2005).”
From Les thérapies de troisième vague dans le traitement du trouble obsessionnel-compulsif: Application de la thérapie d’acceptation et d’engagement (2014) · cites this paper as Cottraux, Bouvard et Milliery, 2005
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References 46 · Cited by 60
- Authors
- Cottraux, J., Bouvard, M. A., & Milliery, M.
- Affiliations
- Université Savoie Mont Blanc (FR)
- Corresponding author
- Cottraux, Jean
- ORCID
- Bouvard, Martine A.
- Venue
- Cognitive Behaviour Therapy
- Publisher
- Informa UK Limited
- Published
- 2005-09-05
- Volume
- 34
- Issue
- 3
- Pages
- 185-192
- ISSN
- 1650-6073 (ISSN-L)
- 1651-2316
- OpenAlex
- W1989303291
- Cited by
- 60
- References
- 46
- Citations by year
- 2024: 2 · 2023: 3 · 2022: 3 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 2 · 2014: 4 · 2013: 2 · 2012: 8
- FWCI
- 0.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cognitive Behaviour Therapy (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- obsessive-compulsive disorder, cognitive behavioral therapy, pharmacotherapy, selective serotonin reuptake inhibitors, combination therapy, treatment efficacy, treatment response, treatment-resistant OCD, clinical decision-making, multidisciplinary treatment
- MeSH terms
- Combined Modality Therapy, Humans, Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy, Treatment Failure, Selective Serotonin Reuptake Inhibitors, Practice Guidelines as Topic
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