The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.
Albumin nanostructures as advanced drug delivery systems
Open accessAbstract
INTRODUCTION: One of the biggest impacts that the nanotechnology has made on medicine and biology, has been in the area of drug delivery systems (DDSs). Many drugs suffer from serious problems concerning insolubility, instability in biological environments, poor uptake into cells and tissues, sub-optimal selectivity for targets and unwanted side effects. Nanocarriers can be designed as DDSs to overcome many of these drawbacks. One of the most versatile building blocks to prepare these nanocarriers is the ubiquitous, readily available and inexpensive protein, serum albumin. Areas covered: This review covers the use of different types of albumin (human, bovine, rat, and chicken egg) to prepare nanoparticle and microparticle-based structures to bind drugs. Various methods have been used to modify the albumin structure. A range of targeting ligands can be attached to the albumin that can be recognized by specific cell receptors that are expressed on target cells or tissues. Expert opinion: The particular advantages of albumin used in DDSs include ready availability, ease of chemical modification, good biocompatibility, and low immunogenicity. The regulatory approvals that have been received for several albumin-based therapeutic agents suggest that this approach will continue to be successfully explored.
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Cites
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Cited by
Karimi, M., Sahandi Zangabad, P., Ghasemi, A., Amiri, M., Bahrami, M., Malekzad, H., Ghahramanzadeh Asl, H., Mahdieh, Z., Bozorgomid, M., Ghasemi, A., et al. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b00371 · Cited by 500
Self-citationNoble metal nanoparticles in biosensors: recent studies and applications
Malekzad, H., Sahandi Zangabad, P., Mirshekari, H., Karimi, M., & Hamblin, M. R. (2017) · Nanotechnology Reviews · doi:10.1515/ntrev-2016-0014 · Cited by 375
Self-citationFarjadian, F., Abbaspour, S., Sadatlu, M. A. A., Mirkiani, S., Ghasemi, A., Hoseini‐Ghahfarokhi, M., Mozaffari, N., Karimi, M., & Hamblin, M. R. (2020) · ChemistrySelect · doi:10.1002/slct.202002501 · Cited by 323
Self-citationStructural and biochemical features of human Serum albumin essential for eukaryotic cell culture
Mishra, V., & Heath, R. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168411 · Cited by 295
Albumin-chaperoned cyanine dye yields superbright NIR-II fluorophore with enhanced pharmacokinetics
Tian, R., Zeng, Q., Zhu, S., Lau, J., Chandra, S., Ertsey, R., Hettie, K. S., Teraphongphom, T., Hu, Z., Niu, G., et al. (2019) · Science Advances · doi:10.1126/sciadv.aaw0672 · Cited by 266
Metadata
- Authors
- Karimi, M., Bahrami, S., Ravari, S. B., Zangabad, P. S., Mirshekari, H., Bozorgomid, M., Shahreza, S., Sori, M., & Hamblin, M. R.
- Venue
- Expert Opinion on Drug Delivery
- Publisher
- Informa UK Limited
- Published
- 2016-06-03
- Volume
- 13
- Issue
- 11
- Pages
- 1609-1623
- ISSN
- 1742-5247 (ISSN-L)
- 1744-7593
- OpenAlex
- W2407297656
- Cited by
- 422
- References
- 110
- FWCI
- 7.64
- Type
- journal article
- Language
- en
- Open access
- green
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- Karimi, M., Bahrami, S., Ravari, S. B., Zangabad, P. S., Mirshekari, H., Bozorgomid, M., Shahreza, S., Sori, M., & Hamblin, M. R. (2016). Albumin nanostructures as advanced drug delivery systems. Expert Opinion on Drug Delivery. https://doi.org/10.1080/17425247.2016.1193149
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