The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
The risk of non-union per fracture: current myths and revised figures from a population of over 4 million adults
Open accessAbstract
Background and purpose - Fracture non-union remains a major clinical problem, yet there are no data available regarding the overall risk of fractures progressing to non-union in a large population. We investigated the rate of non-union per fracture in a large adult population. Methods - National data collected prospectively over a 5-year period and involving just under 5,000 non-unions were analyzed and compared to the incidence of fracture in the same period. Results and interpretation - The overall risk of non-union per fracture was 1.9%, which is considerably less than previously believed. However, for certain fractures in specific age groups the risk of non-union rose to 9%. As expected, these higher rates of non-union were observed with tibial and clavicular fractures, but-less expectedly-it was in the young and middle-aged adults rather than in the older and elderly population. This study is the first to examine fracture non-union rates in a large population according to age and site, and provides more robust (and lower) estimates of non-union risk than those that are frequently quoted.
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Cites
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Tzioupis, C., & Giannoudis, P. V. (2007) · Injury · doi:10.1016/s0020-1383(07)80003-9 · Cited by 374
A Lack of Consensus in the Assessment of Fracture Healing Among Orthopaedic Surgeons
Bhandari, M., Guyatt, G. H., Swiontkowski, M. F., Tornetta, P., Sprague, S., & Schemitsch, E. H. (2002) · Journal of Orthopaedic Trauma · doi:10.1097/00005131-200209000-00004 · Cited by 322
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Cited by
Wu, A.-M., Bisignano, C., James, S. L., Abady, G. G., Abedi, A., Abu-Gharbieh, E., Alhassan, R. K., Alipour, V., Arabloo, J., Asaad, M., et al. (2021) · The Lancet Healthy Longevity · doi:10.1016/s2666-7568(21)00172-0 · Cited by 1,291
The decisive early phase of bone regeneration
Duda, G. N., Geissler, S., Checa, S., Tsitsilonis, S., Petersen, A., & Schmidt-Bleek, K. (2023) · Nature Reviews Rheumatology · doi:10.1038/s41584-022-00887-0 · Cited by 409
Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence
Saul, D., & Khosla, S. (2022) · Endocrine Reviews · doi:10.1210/endrev/bnac008 · Cited by 185
Gait analysis to monitor fracture healing of the lower leg
Warmerdam, E., Orth, M., Pohlemann, T., & Ganse, B. (2023) · Bioengineering · doi:10.3390/bioengineering10020255 · Cited by 47
Single‐cell RNAseq provides insight into altered immune cell populations in human fracture nonunions
Avin, K. G., Dominguez, J. M., Chen, N. X., Hato, T., Myslinski, J. J., Gao, H., Liu, Y., McKinley, T. O., Brown, K. M., Moe, S. M., et al. (2023) · Journal of Orthopaedic Research · doi:10.1002/jor.25452 · Cited by 39
Metadata
- Authors
- Mills, L. A., Aitken, S. A., & Simpson, A. H. R. W.
- Venue
- Acta Orthopaedica
- Published
- 2017-05-16
- Volume
- 88
- Issue
- 4
- Pages
- 434-439
- ISSN
- 1745-3674 (ISSN-L)
- 1745-3682
- OpenAlex
- W2615201841
- Cited by
- 373
- References
- 16
- FWCI
- 12.98
- Type
- journal article
- Language
- en
- Open access
- gold
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- Mills, L. A., Aitken, S. A., & Simpson, A. H. R. W. (2017). The risk of non-union per fracture: current myths and revised figures from a population of over 4 million adults. Acta Orthopaedica. https://doi.org/10.1080/17453674.2017.1321351
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
