Biology of C-Reactive Protein and the Acute Phase Response
Abstract
In the nearly half century since its discovery, interest in CRP has waxed and waned. That interest has now been intensified, both because of recognition that CRP is prototypical of a family of acute phase proteins, including serum amyloid, and because it can now be seen as one of a unique class of proteins that may represent a host defense system that parallels but is distinct from immunologic response.
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References 7 · Cited by 80
- Authors
- Gewurz, H.
- Affiliations
- Rush University Medical Center (US)
- Corresponding author
- Gewurz, Henry
- Venue
- Hospital Practice
- Publisher
- Informa UK Limited
- Published
- 1982-06
- Volume
- 17
- Issue
- 6
- Pages
- 67-81
- ISSN
- 0018-5809 (ISSN-L)
- 2154-8331
- 2377-1003
- OpenAlex
- W150236735
- Cited by
- 80
- References
- 7
- Citations by year
- 2024: 3 · 2023: 6 · 2022: 4 · 2021: 4 · 2020: 2 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 3 · 2014: 1 · 2012: 2
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Hospital Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Biomarkers in Disease Mechanisms
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Life Sciences › Immunology and Microbiology › Immunology › Inflammation biomarkers and pathways
- Keywords
- C-reactive protein, acute phase response, acute phase proteins, serum amyloid, host defense, inflammation, innate immunity
- MeSH terms
- Animals, Blood Sedimentation, C-Reactive Protein, Complement Activation, Erythrocyte Aggregation, Humans, Infections, Inflammation, Isoelectric Point, Liver, Lymphocytes, Microscopy, Electron, Molecular Weight, Opsonin Proteins, Platelet Aggregation, Polymers, Prostaglandins, Protein Binding, Spleen, Wounds and Injuries, Mice
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