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Cited by 331

The DOI matches its Crossref record; 69 of the 69 references it cites were found in a registry or an index.

A review of Dengvaxia®: development to deployment

Open access
Thomas, Stephen J., Yoon, In-Kyu·2019·Human Vaccines & Immunotherapeutics

Abstract

Dengue is the world's most prevalent and important arboviral disease. More than 50% of the world's population lives at daily risk of infection and it is estimated more than 95 million people a year seek medical care following infection. Severe disease can manifest as plasma leakage and potential for clinically significant hemorrhage, shock, and death. Treatment is supportive and there is currently no licensed anti-dengue virus prophylactic or therapeutic compound. A single dengue vaccine, Sanofi Pasteur's Dengvaxia®, has been licensed in 20 countries but uptake has been poor. A safety signal in dengue seronegative vaccine recipients stimulated an international re-look at the vaccine performance profile, new World Health Organization recommendations for use, and controversy in the Philippines involving the government, regulatory agencies, Sanofi Pasteur, clinicians responsible for testing and administering the vaccine, and the parents of vaccinated children. In this review, we provide an overview of Dengvaxia's® development and discuss what has been learned about product performance since its licensure.

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Metadata

Authors
Thomas, S. J., & Yoon, I.-K.
Venue
Human Vaccines & Immunotherapeutics
Published
2019-10-03
Volume
15
Issue
10
Pages
2295-2314
ISSN
  • 2164-5515 (ISSN-L)
  • 2164-554X
OpenAlex
W2978577943
Cited by
331
References
69
FWCI
31.62
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: A review of Dengvaxia®: development to deployment. https://app.cochat.ai/papers/10.1080/21645515.2019.1658503
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Thomas, S. J., & Yoon, I.-K. (2019). A review of Dengvaxia®: development to deployment. Human Vaccines & Immunotherapeutics. https://doi.org/10.1080/21645515.2019.1658503

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